Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 13346..13923 Replicon plasmid unnsmrf
Accession NZ_CP009363
Organism Yersinia frederiksenii Y225

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag AW19_RS00090 Protein ID WP_042562281.1
Coordinates 13621..13923 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AW19_RS00085 Protein ID WP_042562280.1
Coordinates 13346..13624 (-) Length 93 a.a.

Genomic Context

AW19_RS00065AW19_RS00070AW19_RS00075AW19_RS00080AW19_RS00095AW19_RS00115AW19_RS00085AW19_RS00090AW19_RS00100AW19_RS00105AW19_RS00110
Location: 10520..11035 (516 bp)
Type: Others
Protein ID: WP_042562276.1
Location: 11088..11633 (546 bp)
Type: Others
Protein ID: WP_042562277.1
Location: 11692..11982 (291 bp)
Type: Others
Protein ID: WP_042562278.1
Location: 11998..12201 (204 bp)
Type: Others
Protein ID: WP_042562279.1
Location: 14175..14621 (447 bp)
Type: Others
Protein ID: WP_042562282.1
Location: 17412..17759 (348 bp)
Type: Others
Protein ID: WP_042562286.1
Location: 13346..13624 (279 bp)
Type: Antitoxin
Protein ID: WP_042562280.1
Location: 13621..13923 (303 bp)
Type: Toxin
Protein ID: WP_042562281.1
Location: 14949..15683 (735 bp)
Type: Others
Protein ID: WP_042562283.1
Location: 15739..16452 (714 bp)
Type: Others
Protein ID: WP_042562284.1
Location: 16449..17102 (654 bp)
Type: Others
Protein ID: WP_042562285.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AW19_RS0006510520..11035+516WP_042562276.1J domain-containing protein-
AW19_RS0007011088..11633+546WP_042562277.1hypothetical protein-
AW19_RS0007511692..11982+291WP_042562278.1hypothetical protein-
AW19_RS0008011998..12201+204WP_042562279.1helix-turn-helix domain-containing protein-
AW19_RS0008513346..13624-279WP_042562280.1putative addiction module antidote proteinAntitoxin
AW19_RS0009013621..13923-303WP_042562281.1type II toxin-antitoxin system RelE/ParE family toxinToxin
AW19_RS0009514175..14621+447WP_042562282.1hypothetical protein-
AW19_RS0010014949..15683-735WP_042562283.1hypothetical protein-
AW19_RS0010515739..16452-714WP_042562284.1hypothetical protein-
AW19_RS0011016449..17102-654WP_042562285.1hypothetical protein-
AW19_RS0011517412..17759+348WP_042562286.1plasmid mobilization relaxosome protein MobC-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..5536255362


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-87)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11228.00 Da        Isoelectric Point: 9.8105

>T48807 WP_042562281.1 NZ_CP009363:c13923-13621 [Yersinia frederiksenii Y225]
MITVLSTETFDTWIDALKDIRAKTKIQARIRRLKNGNFGDIEPVGEGFSEMRIHEGKGYRVYLKSHGSIIVVLLCGGDKS
TQQKDITKAKAIYKSIEGEL

Download         Length: 303 bp

>T48807 NZ_CP009363:c13923-13621 [Yersinia frederiksenii Y225]
ATGATAACTGTATTAAGTACGGAAACATTTGATACTTGGATTGATGCCCTAAAAGACATTAGGGCTAAGACAAAAATTCA
GGCACGTATTCGCAGACTGAAAAACGGAAATTTTGGCGATATAGAGCCAGTAGGTGAAGGGTTTTCAGAAATGCGTATTC
ATGAAGGGAAAGGGTACAGGGTTTATCTGAAAAGCCACGGAAGTATTATCGTTGTTTTGCTTTGTGGGGGCGATAAAAGC
ACACAGCAAAAAGATATCACCAAAGCTAAGGCAATCTATAAATCAATCGAGGGGGAGCTATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10157.72 Da        Isoelectric Point: 5.6105

>AT48807 WP_042562280.1 NZ_CP009363:c13624-13346 [Yersinia frederiksenii Y225]
MKLKEYDIAEHLNSEEEMQMYLNEILEDGDPALVLSALGDIARAKNMSQLSREVGMSREGLYHALSGKGNPTFSAMMKIT
KALGLKLHFTGA

Download         Length: 279 bp

>AT48807 NZ_CP009363:c13624-13346 [Yersinia frederiksenii Y225]
ATGAAGCTGAAAGAATACGATATTGCAGAGCACTTAAATAGTGAAGAAGAAATGCAAATGTACCTTAACGAAATTTTGGA
AGATGGAGATCCAGCGTTGGTACTCTCTGCACTTGGGGATATAGCCAGAGCAAAAAATATGAGCCAGCTTTCGAGAGAGG
TTGGTATGTCAAGAGAGGGGCTATATCACGCCCTTTCAGGGAAAGGAAATCCAACATTCAGCGCTATGATGAAAATAACG
AAAGCTCTAGGGCTTAAACTTCATTTCACAGGTGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References