Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /SpoIISA(toxin) |
Location | 4843985..4844960 | Replicon | chromosome |
Accession | NZ_CP009341 | ||
Organism | Bacillus anthracis strain Ohio ACB |
Toxin (Protein)
Gene name | spoIISA | Uniprot ID | A0A2R2IKP2 |
Locus tag | BG02_RS27245 | Protein ID | WP_002036394.1 |
Coordinates | 4843985..4844722 (+) | Length | 246 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | R8HWP4 |
Locus tag | BG02_RS27250 | Protein ID | WP_000588712.1 |
Coordinates | 4844835..4844960 (+) | Length | 42 a.a. |
Genomic Context
Location: 4839713..4840495 (783 bp)
Type: Others
Protein ID: WP_000381787.1
Type: Others
Protein ID: WP_000381787.1
Location: 4842409..4842891 (483 bp)
Type: Others
Protein ID: WP_000191911.1
Type: Others
Protein ID: WP_000191911.1
Location: 4843059..4843796 (738 bp)
Type: Others
Protein ID: WP_000594139.1
Type: Others
Protein ID: WP_000594139.1
Location: 4843985..4844722 (738 bp)
Type: Toxin
Protein ID: WP_002036394.1
Type: Toxin
Protein ID: WP_002036394.1
Location: 4844835..4844960 (126 bp)
Type: Antitoxin
Protein ID: WP_000588712.1
Type: Antitoxin
Protein ID: WP_000588712.1
Location: 4845037..4845213 (177 bp)
Type: Others
Protein ID: WP_000852614.1
Type: Others
Protein ID: WP_000852614.1
Location: 4846383..4846559 (177 bp)
Type: Others
Protein ID: WP_000808045.1
Type: Others
Protein ID: WP_000808045.1
Location: 4846703..4848172 (1470 bp)
Type: Others
Protein ID: WP_000287522.1
Type: Others
Protein ID: WP_000287522.1
Location: 4840617..4842302 (1686 bp)
Type: Others
Protein ID: WP_009879073.1
Type: Others
Protein ID: WP_009879073.1
Location: 4845250..4845531 (282 bp)
Type: Others
Protein ID: WP_001041555.1
Type: Others
Protein ID: WP_001041555.1
Location: 4845808..4846044 (237 bp)
Type: Others
Protein ID: WP_001021689.1
Type: Others
Protein ID: WP_001021689.1
Location: 4848736..4849206 (471 bp)
Type: Others
Protein ID: WP_000670597.1
Type: Others
Protein ID: WP_000670597.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BG02_RS27225 | 4839713..4840495 | + | 783 | WP_000381787.1 | class I SAM-dependent methyltransferase | - |
BG02_RS27230 | 4840617..4842302 | - | 1686 | WP_009879073.1 | alpha-keto acid decarboxylase family protein | - |
BG02_RS27235 | 4842409..4842891 | + | 483 | WP_000191911.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
BG02_RS27240 | 4843059..4843796 | + | 738 | WP_000594139.1 | 2,3-diphosphoglycerate-dependent phosphoglycerate mutase | - |
BG02_RS27245 | 4843985..4844722 | + | 738 | WP_002036394.1 | type II toxin-antitoxin system SpoIISA family toxin | Toxin |
BG02_RS27250 | 4844835..4844960 | + | 126 | WP_000588712.1 | hypothetical protein | Antitoxin |
BG02_RS32275 | 4845037..4845213 | + | 177 | WP_000852614.1 | hypothetical protein | - |
BG02_RS27260 | 4845250..4845531 | - | 282 | WP_001041555.1 | hypothetical protein | - |
BG02_RS27265 | 4845808..4846044 | - | 237 | WP_001021689.1 | hypothetical protein | - |
BG02_RS32280 | 4846383..4846559 | + | 177 | WP_000808045.1 | hypothetical protein | - |
BG02_RS27275 | 4846703..4848172 | + | 1470 | WP_000287522.1 | beta-Ala-His dipeptidase | - |
BG02_RS27280 | 4848736..4849206 | - | 471 | WP_000670597.1 | DUF5065 family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 246 a.a. Molecular weight: 28373.03 Da Isoelectric Point: 8.2705
>T48781 WP_002036394.1 NZ_CP009341:4843985-4844722 [Bacillus anthracis]
VISNIRIGLFILAIVFLVLVFFYWRNEELYEEKKQRIRKTWYGLFIVSVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSTIIPLEYIEQLNEQRAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK
VISNIRIGLFILAIVFLVLVFFYWRNEELYEEKKQRIRKTWYGLFIVSVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSTIIPLEYIEQLNEQRAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK
Download Length: 738 bp
>T48781 NZ_CP009341:4843985-4844722 [Bacillus anthracis]
GTGATCTCTAACATTCGAATCGGCTTATTTATTTTAGCAATCGTTTTTCTAGTTCTTGTTTTCTTTTACTGGAGAAATGA
AGAATTGTATGAGGAGAAGAAGCAACGAATTAGAAAGACTTGGTATGGGTTGTTTATAGTATCAGTCACCGTGTATTTCA
TGATAAAAGGAATCGATTTAACCCTCTGGAAAAATCTTTTAATGTTCACTGCAATGGTTATTTTCGTTGATATTGCATTT
ATTTTAACACCTAATATTTCAGAAATATGGGGAGCGAAATTTAGCGATATCGGCAAGACGGTTCAATCGATAAAACGGTC
ATTAATTGCTTCTAAAGCAAGAGGAGAAATATACACAACAATCATTCAAAATGTCAATCCAGCAGTGTTCGGTACGATGG
AATGGCATACGGAGGAAGAATATACAAAAAGCTTAAACGCATTTTTAGATTCGTATGGGGAAAAGATTGGAGCAAAAATT
GTTGTATTTGAAGCGGCAAAGGAATTAAATACAAACTTTCGTGGTATCCGTTCTCAATTTAGTACGATTATTCCGTTAGA
GTACATTGAGCAATTGAATGAGCAGAGAGCAGTACAAGTAGAAAATGTCGGAATTATACCAGCAAAAATAGTGAGTGATG
TTTTCATTGTTATTGATGGGAAGAAAAATAACCTGCAAGATCGAGATTTTGAAAATGTATATAATTTAACAATACATCAT
AGTTATTTTAGTAAATAA
GTGATCTCTAACATTCGAATCGGCTTATTTATTTTAGCAATCGTTTTTCTAGTTCTTGTTTTCTTTTACTGGAGAAATGA
AGAATTGTATGAGGAGAAGAAGCAACGAATTAGAAAGACTTGGTATGGGTTGTTTATAGTATCAGTCACCGTGTATTTCA
TGATAAAAGGAATCGATTTAACCCTCTGGAAAAATCTTTTAATGTTCACTGCAATGGTTATTTTCGTTGATATTGCATTT
ATTTTAACACCTAATATTTCAGAAATATGGGGAGCGAAATTTAGCGATATCGGCAAGACGGTTCAATCGATAAAACGGTC
ATTAATTGCTTCTAAAGCAAGAGGAGAAATATACACAACAATCATTCAAAATGTCAATCCAGCAGTGTTCGGTACGATGG
AATGGCATACGGAGGAAGAATATACAAAAAGCTTAAACGCATTTTTAGATTCGTATGGGGAAAAGATTGGAGCAAAAATT
GTTGTATTTGAAGCGGCAAAGGAATTAAATACAAACTTTCGTGGTATCCGTTCTCAATTTAGTACGATTATTCCGTTAGA
GTACATTGAGCAATTGAATGAGCAGAGAGCAGTACAAGTAGAAAATGTCGGAATTATACCAGCAAAAATAGTGAGTGATG
TTTTCATTGTTATTGATGGGAAGAAAAATAACCTGCAAGATCGAGATTTTGAAAATGTATATAATTTAACAATACATCAT
AGTTATTTTAGTAAATAA
Antitoxin
Download Length: 42 a.a. Molecular weight: 4938.34 Da Isoelectric Point: 3.9150
>AT48781 WP_000588712.1 NZ_CP009341:4844835-4844960 [Bacillus anthracis]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEELEEELKRK
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEELEEELKRK
Download Length: 126 bp
>AT48781 NZ_CP009341:4844835-4844960 [Bacillus anthracis]
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGATAATGAAGATACAACAGATTTCTCGTTAATAAAAGGAGATAC
ATTACAGCAAGTAGAAGAATTAGAAGAAGAATTAAAAAGAAAATGA
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGATAATGAAGATACAACAGATTTCTCGTTAATAAAAGGAGATAC
ATTACAGCAAGTAGAAGAATTAGAAGAAGAATTAAAAAGAAAATGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2R2IKP2 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A366GQT1 |