Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 352664..353902 | Replicon | chromosome |
| Accession | NZ_CP009323 | ||
| Organism | Burkholderia gladioli strain ATCC 10248 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A808W951 |
| Locus tag | BM43_RS18405 | Protein ID | WP_036049937.1 |
| Coordinates | 352664..353248 (-) | Length | 195 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | BM43_RS18410 | Protein ID | WP_196788438.1 |
| Coordinates | 353351..353902 (-) | Length | 184 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BM43_RS18380 | 348438..348854 | + | 417 | WP_036053101.1 | DUF302 domain-containing protein | - |
| BM43_RS18385 | 348979..349941 | - | 963 | WP_036040951.1 | AraC family transcriptional regulator | - |
| BM43_RS41965 | 350136..350954 | - | 819 | WP_052710575.1 | lytic transglycosylase domain-containing protein | - |
| BM43_RS18395 | 351359..352105 | - | 747 | WP_052409298.1 | hypothetical protein | - |
| BM43_RS18405 | 352664..353248 | - | 585 | WP_036049937.1 | HD domain-containing protein | Toxin |
| BM43_RS18410 | 353351..353902 | - | 552 | WP_196788438.1 | helix-turn-helix domain-containing protein | Antitoxin |
| BM43_RS18415 | 354098..354361 | - | 264 | WP_013698802.1 | PAAR domain-containing protein | - |
| BM43_RS18420 | 354428..354851 | - | 424 | Protein_334 | hypothetical protein | - |
| BM43_RS18425 | 354895..356910 | - | 2016 | WP_036049934.1 | VC_2705 family sodium/solute symporter | - |
| BM43_RS18430 | 356904..357341 | - | 438 | WP_080742279.1 | DUF4212 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 195 a.a. Molecular weight: 21529.30 Da Isoelectric Point: 5.0096
>T48768 WP_036049937.1 NZ_CP009323:c353248-352664 [Burkholderia gladioli]
MDDALIDARLDFLRGCERLKDVLRSGHTSGGRRESTAEHSWRLALMAMVLMDQLGEVDPGRVLELCLVHDLGEALGGDVP
APEQAPGSDKDAAERRDLLRLGDALDAPMRERIVALWDEYARAATPEARAVKALDKIETILQHTQGENPPDFDYAFNLAY
GQAHTRKVPALQRFRERVDEATRERMARAGGPSC
MDDALIDARLDFLRGCERLKDVLRSGHTSGGRRESTAEHSWRLALMAMVLMDQLGEVDPGRVLELCLVHDLGEALGGDVP
APEQAPGSDKDAAERRDLLRLGDALDAPMRERIVALWDEYARAATPEARAVKALDKIETILQHTQGENPPDFDYAFNLAY
GQAHTRKVPALQRFRERVDEATRERMARAGGPSC
Download Length: 585 bp
>T48768 NZ_CP009323:c353248-352664 [Burkholderia gladioli]
ATGGACGACGCGTTGATCGACGCACGACTGGATTTCCTGCGCGGCTGCGAGCGCCTGAAGGATGTGCTGCGCAGCGGCCA
TACCTCGGGCGGGCGACGCGAGAGCACGGCCGAGCACAGCTGGCGGCTCGCGCTGATGGCGATGGTGCTGATGGATCAAT
TGGGCGAGGTCGACCCCGGCAGGGTGCTCGAGCTCTGCCTGGTGCATGACCTGGGCGAAGCGCTGGGCGGCGACGTGCCG
GCGCCCGAGCAGGCCCCGGGCAGCGACAAGGATGCCGCCGAGCGACGCGACCTGCTGCGCCTCGGCGACGCGCTCGATGC
GCCGATGCGCGAGAGGATCGTCGCGTTGTGGGACGAGTATGCGCGGGCGGCCACGCCGGAAGCACGCGCGGTGAAGGCGC
TCGACAAGATCGAGACGATCCTGCAGCACACGCAGGGCGAGAATCCGCCCGATTTCGACTATGCGTTCAACCTCGCGTAT
GGACAGGCGCATACCCGCAAGGTGCCGGCGCTGCAGCGGTTTCGCGAGCGCGTCGACGAGGCGACGCGCGAGCGGATGGC
CCGTGCTGGCGGGCCTTCGTGCTGA
ATGGACGACGCGTTGATCGACGCACGACTGGATTTCCTGCGCGGCTGCGAGCGCCTGAAGGATGTGCTGCGCAGCGGCCA
TACCTCGGGCGGGCGACGCGAGAGCACGGCCGAGCACAGCTGGCGGCTCGCGCTGATGGCGATGGTGCTGATGGATCAAT
TGGGCGAGGTCGACCCCGGCAGGGTGCTCGAGCTCTGCCTGGTGCATGACCTGGGCGAAGCGCTGGGCGGCGACGTGCCG
GCGCCCGAGCAGGCCCCGGGCAGCGACAAGGATGCCGCCGAGCGACGCGACCTGCTGCGCCTCGGCGACGCGCTCGATGC
GCCGATGCGCGAGAGGATCGTCGCGTTGTGGGACGAGTATGCGCGGGCGGCCACGCCGGAAGCACGCGCGGTGAAGGCGC
TCGACAAGATCGAGACGATCCTGCAGCACACGCAGGGCGAGAATCCGCCCGATTTCGACTATGCGTTCAACCTCGCGTAT
GGACAGGCGCATACCCGCAAGGTGCCGGCGCTGCAGCGGTTTCGCGAGCGCGTCGACGAGGCGACGCGCGAGCGGATGGC
CCGTGCTGGCGGGCCTTCGTGCTGA
Antitoxin
Download Length: 184 a.a. Molecular weight: 20143.87 Da Isoelectric Point: 8.3940
>AT48768 WP_196788438.1 NZ_CP009323:c353902-353351 [Burkholderia gladioli]
MPPSALACSPGASLRRWRTLRRIKQEHAAALFGVSQSTISRWEAGTQAVSHEELRRIEACLSARLDSAADRALERLVSHH
TRPVHLVCDLTHRLLACSAPRAAEFAAPLSSLMGASLWPFATAEIVAREQSLRDAGWQDHPAPSIEFDTGSNDSPQVPIR
ASRCRWTRFTLSDGTLARLVETL
MPPSALACSPGASLRRWRTLRRIKQEHAAALFGVSQSTISRWEAGTQAVSHEELRRIEACLSARLDSAADRALERLVSHH
TRPVHLVCDLTHRLLACSAPRAAEFAAPLSSLMGASLWPFATAEIVAREQSLRDAGWQDHPAPSIEFDTGSNDSPQVPIR
ASRCRWTRFTLSDGTLARLVETL
Download Length: 552 bp
>AT48768 NZ_CP009323:c353902-353351 [Burkholderia gladioli]
TTGCCGCCGTCCGCGCTGGCCTGTTCGCCGGGCGCGAGCTTGCGTCGATGGCGCACGCTGCGCCGGATCAAGCAGGAACA
TGCAGCGGCGCTGTTCGGCGTATCGCAGTCGACGATATCGCGCTGGGAAGCCGGCACGCAGGCGGTGTCGCACGAGGAAC
TGCGGCGCATCGAGGCCTGCTTGTCGGCGCGCCTCGACTCGGCGGCGGATCGCGCGCTCGAGCGCCTCGTCAGCCATCAC
ACCCGTCCCGTTCATCTCGTCTGCGACCTCACGCACCGGCTGCTGGCCTGCTCCGCGCCGCGAGCCGCGGAGTTCGCGGC
GCCGCTGTCGTCGCTGATGGGCGCGTCGCTCTGGCCGTTCGCGACGGCCGAGATCGTGGCGCGCGAGCAGTCGTTGCGCG
ATGCGGGCTGGCAAGATCATCCGGCACCCTCGATCGAATTCGATACCGGGTCCAACGATTCGCCTCAGGTGCCGATTCGT
GCGAGCCGCTGCCGCTGGACGCGTTTCACCTTGTCCGACGGGACGCTGGCGCGCCTGGTCGAGACGCTTTGA
TTGCCGCCGTCCGCGCTGGCCTGTTCGCCGGGCGCGAGCTTGCGTCGATGGCGCACGCTGCGCCGGATCAAGCAGGAACA
TGCAGCGGCGCTGTTCGGCGTATCGCAGTCGACGATATCGCGCTGGGAAGCCGGCACGCAGGCGGTGTCGCACGAGGAAC
TGCGGCGCATCGAGGCCTGCTTGTCGGCGCGCCTCGACTCGGCGGCGGATCGCGCGCTCGAGCGCCTCGTCAGCCATCAC
ACCCGTCCCGTTCATCTCGTCTGCGACCTCACGCACCGGCTGCTGGCCTGCTCCGCGCCGCGAGCCGCGGAGTTCGCGGC
GCCGCTGTCGTCGCTGATGGGCGCGTCGCTCTGGCCGTTCGCGACGGCCGAGATCGTGGCGCGCGAGCAGTCGTTGCGCG
ATGCGGGCTGGCAAGATCATCCGGCACCCTCGATCGAATTCGATACCGGGTCCAACGATTCGCCTCAGGTGCCGATTCGT
GCGAGCCGCTGCCGCTGGACGCGTTTCACCTTGTCCGACGGGACGCTGGCGCGCCTGGTCGAGACGCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|