Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 3883476..3884051 Replicon chromosome
Accession NZ_CP009322
Organism Burkholderia gladioli strain ATCC 10248

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BM43_RS16695 Protein ID WP_036054553.1
Coordinates 3883764..3884051 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A560UNM0
Locus tag BM43_RS16690 Protein ID WP_036030606.1
Coordinates 3883476..3883760 (-) Length 95 a.a.

Genomic Context

BM43_RS16675BM43_RS16680BM43_RS16685BM43_RS16705BM43_RS16715BM43_RS16670BM43_RS16690BM43_RS16695BM43_RS16700BM43_RS16710
Location: 3879993..3881630 (1638 bp)
Type: Others
Protein ID: WP_036054559.1
Location: 3881816..3882943 (1128 bp)
Type: Others
Protein ID: WP_167547494.1
Location: 3883092..3883418 (327 bp)
Type: Others
Protein ID: WP_036054555.1
Location: 3885279..3885749 (471 bp)
Type: Others
Protein ID: WP_013689305.1
Location: 3886874..3887935 (1062 bp)
Type: Others
Protein ID: WP_013689307.1
Location: 3878574..3879857 (1284 bp)
Type: Others
Protein ID: WP_013689299.1
Location: 3883476..3883760 (285 bp)
Type: Antitoxin
Protein ID: WP_036030606.1
Location: 3883764..3884051 (288 bp)
Type: Toxin
Protein ID: WP_036054553.1
Location: 3884184..3885122 (939 bp)
Type: Others
Protein ID: WP_036054551.1
Location: 3885793..3886629 (837 bp)
Type: Others
Protein ID: WP_036054549.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BM43_RS166703878574..3879857-1284WP_013689299.14-aminobutyrate--2-oxoglutarate transaminase-
BM43_RS166753879993..3881630+1638WP_036054559.1PLP-dependent aminotransferase family protein-
BM43_RS166803881816..3882943+1128WP_167547494.1ABC transporter substrate-binding protein-
BM43_RS166853883092..3883418+327WP_036054555.1hypothetical protein-
BM43_RS166903883476..3883760-285WP_036030606.1putative addiction module antidote proteinAntitoxin
BM43_RS166953883764..3884051-288WP_036054553.1type II toxin-antitoxin system RelE/ParE family toxinToxin
BM43_RS167003884184..3885122-939WP_036054551.12-dehydropantoate 2-reductase-
BM43_RS167053885279..3885749+471WP_013689305.1Lrp/AsnC family transcriptional regulator-
BM43_RS167103885793..3886629-837WP_036054549.1DMT family transporter-
BM43_RS167153886874..3887935+1062WP_013689307.1selenide, water dikinase SelD-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-94)

Antitoxin

Uncharacterized protein HI1420

(11-89)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10959.72 Da        Isoelectric Point: 10.4966

>T48767 WP_036054553.1 NZ_CP009322:c3884051-3883764 [Burkholderia gladioli]
MLRSSEFTNWLSSLRDQRGKARIAARLISAQLGNFGEYRVIGEGVREMKVDFGPGYRIYYVRRAEIVYVLLCGGDKSTQK
KDIKRALQMARELKE

Download         Length: 288 bp

>T48767 NZ_CP009322:c3884051-3883764 [Burkholderia gladioli]
TTGCTGCGCTCCAGTGAATTCACAAACTGGCTTTCCAGCCTGCGTGATCAGCGCGGCAAAGCCCGAATCGCCGCACGCCT
GATCAGTGCCCAGCTAGGCAATTTTGGCGAGTACCGCGTGATAGGCGAAGGCGTCCGCGAAATGAAGGTCGACTTCGGGC
CGGGTTATCGCATCTACTATGTCCGTCGCGCCGAGATCGTCTATGTCCTTCTCTGCGGTGGCGATAAATCTACACAGAAA
AAAGACATCAAGCGCGCGCTCCAGATGGCGCGCGAACTGAAGGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10072.47 Da        Isoelectric Point: 5.0484

>AT48767 WP_036030606.1 NZ_CP009322:c3883760-3883476 [Burkholderia gladioli]
MPDYAEFDAADYLDNDETVAEFLAVAAEDPDPAVFLAAVAAVARARGMTKVASEAGLGRVTLHKALTPGAHPRYETVQKI
LRSLGLRMTFTVAH

Download         Length: 285 bp

>AT48767 NZ_CP009322:c3883760-3883476 [Burkholderia gladioli]
ATGCCCGATTACGCCGAATTCGATGCGGCCGACTATCTCGACAATGACGAAACCGTGGCGGAATTTCTCGCGGTTGCGGC
AGAGGATCCCGATCCCGCAGTGTTCCTTGCTGCCGTGGCCGCTGTCGCACGCGCGCGCGGGATGACCAAGGTGGCGTCGG
AAGCCGGCCTTGGACGGGTCACCTTGCACAAGGCGCTGACGCCTGGCGCTCACCCTCGATATGAGACCGTGCAGAAGATC
CTGCGCTCGCTGGGCCTTCGCATGACCTTCACCGTCGCCCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A560UNM0

References