Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1987368..1988010 Replicon chromosome
Accession NZ_CP009322
Organism Burkholderia gladioli strain ATCC 10248

Toxin (Protein)


Gene name vapC Uniprot ID A0A808W1S4
Locus tag BM43_RS08955 Protein ID WP_036055816.1
Coordinates 1987368..1987790 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A808W4F3
Locus tag BM43_RS08960 Protein ID WP_036033948.1
Coordinates 1987777..1988010 (-) Length 78 a.a.

Genomic Context

BM43_RS08935BM43_RS08940BM43_RS08950BM43_RS08970BM43_RS08975BM43_RS08945BM43_RS08955BM43_RS08960BM43_RS08965
Location: 1983168..1984541 (1374 bp)
Type: Others
Protein ID: WP_036055820.1
Location: 1984544..1985626 (1083 bp)
Type: Others
Protein ID: WP_036055819.1
Location: 1986566..1987246 (681 bp)
Type: Others
Protein ID: WP_036055817.1
Location: 1989903..1991669 (1767 bp)
Type: Others
Protein ID: WP_036055814.1
Location: 1991794..1992042 (249 bp)
Type: Others
Protein ID: WP_013690725.1
Location: 1985646..1986416 (771 bp)
Type: Others
Protein ID: WP_036055818.1
Location: 1987368..1987790 (423 bp)
Type: Toxin
Protein ID: WP_036055816.1
Location: 1987777..1988010 (234 bp)
Type: Antitoxin
Protein ID: WP_036033948.1
Location: 1988326..1989315 (990 bp)
Type: Others
Protein ID: WP_036055815.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BM43_RS089351983168..1984541+1374WP_036055820.1L-fucose:H+ symporter permease-
BM43_RS089401984544..1985626+1083WP_036055819.1aldose 1-epimerase family protein-
BM43_RS089451985646..1986416-771WP_036055818.1DNA-binding transcriptional repressor DeoR-
BM43_RS089501986566..1987246+681WP_036055817.1deoxyribose-phosphate aldolase-
BM43_RS089551987368..1987790-423WP_036055816.1type II toxin-antitoxin system VapC family toxinToxin
BM43_RS089601987777..1988010-234WP_036033948.1DNA-binding proteinAntitoxin
BM43_RS089651988326..1989315-990WP_036055815.1LysR family transcriptional regulator-
BM43_RS089701989903..1991669+1767WP_036055814.1AMP-binding protein-
BM43_RS089751991794..1992042+249WP_013690725.1acyl carrier protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15659.95 Da        Isoelectric Point: 8.5438

>T48766 WP_036055816.1 NZ_CP009322:c1987790-1987368 [Burkholderia gladioli]
MYLIDTNVVSEVRKRDRADKGVMAFFRQAARDDAGLYLSVVTVGELRRGVEIIRHRGDESQATRLANWLDGVLREFAANI
LVVDKEIGQMWGYLRVPRPEHSLDKVIAATALIHDLTVVTRNVDDFAGTGARVLNPFKGP

Download         Length: 423 bp

>T48766 NZ_CP009322:c1987790-1987368 [Burkholderia gladioli]
ATGTATTTGATTGACACCAATGTGGTCAGCGAAGTCCGGAAACGGGATCGTGCGGACAAGGGTGTGATGGCCTTCTTTCG
CCAGGCGGCCCGCGACGATGCCGGCCTGTACCTGTCGGTGGTGACGGTGGGCGAACTGCGGCGAGGTGTGGAAATCATCC
GTCACCGTGGCGACGAATCCCAGGCAACGCGTCTCGCGAACTGGCTCGATGGCGTGCTCCGGGAGTTTGCCGCGAACATT
CTCGTGGTGGACAAGGAGATCGGGCAGATGTGGGGCTACCTGCGTGTACCTCGCCCGGAACACTCGCTGGATAAGGTGAT
CGCCGCCACGGCCTTGATTCACGATCTGACCGTGGTGACGCGCAACGTGGATGATTTCGCCGGAACCGGTGCCCGTGTGC
TGAACCCGTTCAAGGGCCCATAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8484.61 Da        Isoelectric Point: 5.5741

>AT48766 WP_036033948.1 NZ_CP009322:c1988010-1987777 [Burkholderia gladioli]
MANLLVRNVDEMLVQILRERAAAHGHSAEAEHRAILARALREPQRKTFAQVLMGMPNVGSDADFARVDDGEAANVFD

Download         Length: 234 bp

>AT48766 NZ_CP009322:c1988010-1987777 [Burkholderia gladioli]
ATGGCGAATCTTCTGGTGAGAAACGTGGACGAAATGCTTGTTCAAATCTTGCGCGAGCGGGCTGCCGCTCACGGGCACAG
CGCGGAAGCCGAGCATCGTGCAATCCTGGCAAGGGCGCTGCGCGAGCCGCAACGCAAGACATTCGCGCAAGTGCTGATGG
GCATGCCGAACGTCGGTAGCGATGCCGATTTTGCGCGCGTGGACGATGGCGAGGCGGCGAATGTATTTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A808W1S4

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A808W4F3

References