Detailed information of TA system TA048747

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbE-relB/ParE-YafN
• Location: 6498262..6498778
• Replicon: chromosome
• Accession: NZ_CP009290
• Organism: Pseudomonas chlororaphis subsp. aurantiaca strain JD37

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: A0A8A9Z863
• Locus tag: JM49_RS29115
• Protein ID: WP_028681510.1
• Coordinates: 6498262..6498543 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JM49_RS30895
• Protein ID: WP_023969916.1
• Coordinates: 6498533..6498778 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JM49_RS29095	6494512..6495408	-	897	WP_038583155.1	HlyD family secretion protein	-
JM49_RS29100	6495405..6495614	-	210	WP_007932080.1	DUF1656 domain-containing protein	-
JM49_RS29105	6495611..6497695	-	2085	WP_038583157.1	FUSC family protein	-
JM49_RS29110	6497692..6498129	-	438	WP_038583159.1	winged helix DNA-binding protein	-
JM49_RS29115	6498262..6498543	-	282	WP_028681510.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JM49_RS30895	6498533..6498778	-	246	WP_023969916.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
JM49_RS29125	6498843..6499088	-	246	WP_023969915.1	DUF2789 domain-containing protein	-
JM49_RS29130	6499219..6499680	-	462	WP_016705004.1	YbaK/EbsC family protein	-
JM49_RS29135	6499904..6501289	+	1386	WP_038583163.1	nodulation protein NfeD	-
JM49_RS29140	6501291..6502049	+	759	WP_038583164.1	slipin family protein	-
JM49_RS29145	6502015..6503010	-	996	WP_038583165.1	aspartyl beta-hydroxylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-70)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10907.82 Da
• Isoelectric Point: 10.6258

>T48747 WP_028681510.1 NZ_CP009290:c6498543-6498262 [Pseudomonas chlororaphis subsp. aurantiaca]
MTYKLQFLPSARKEWDKLGHTLREQFKRKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Nucleotide

• Length: 282 bp

>T48747 NZ_CP009290:c6498543-6498262 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGACTTATAAGCTCCAGTTTCTGCCTTCGGCGCGCAAGGAATGGGACAAGCTCGGTCATACCCTGCGCGAGCAATTCAA
GAGGAAGCTGGCCGAGCGCCTGGAAATGCCACGGGTGCCCGCGGACGCCCTTCACGGTATGGCGGACTGCTACAAGATCA
AGCTCAAGGCCTCTGGCTATCGCCTGGTTTACCAAGTGATCGAGGATCAGGTCGTGGTTTCGGTGGTGGCCGTGGGCAAA
CGTGAACGCAGTGCCGTGTATGAGCGGGCACGAAAGCGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8840.18 Da
• Isoelectric Point: 4.7164

>AT48747 WP_023969916.1 NZ_CP009290:c6498778-6498533 [Pseudomonas chlororaphis subsp. aurantiaca]
MQSVLADKAVSVSELKKNPSAVLNGAQGGPVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Nucleotide

• Length: 246 bp

>AT48747 NZ_CP009290:c6498778-6498533 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGCAAAGCGTATTGGCTGATAAAGCTGTCAGCGTGTCTGAACTGAAAAAAAATCCTTCGGCTGTCCTGAACGGCGCACA
GGGTGGTCCGGTTGCGGTGCTCAATCACAACCGGGTCATGGGCTATATGGTCCCGGCCGACGTGTTTGAAGCCATGATGG
AGCGTCTTGACGATCTTGAACTGGCGGAGATTGTCCGTGCCCGTCGTCACGAGACCCCGGTCCCGGTAAATCTGGATGAC
TTATAA

Structures

Toxin

• AlphaFold DB: A0A8A9Z863