Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 832158..832747 Replicon chromosome
Accession NZ_CP009290
Organism Pseudomonas chlororaphis subsp. aurantiaca strain JD37

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JM49_RS03800 Protein ID WP_038575453.1
Coordinates 832158..832457 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag JM49_RS03805 Protein ID WP_038575454.1
Coordinates 832454..832747 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JM49_RS03770 827639..828526 - 888 WP_038575447.1 (2E,6E)-farnesyl diphosphate synthase -
JM49_RS03775 828523..828765 - 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
JM49_RS03780 828991..830082 + 1092 WP_038575449.1 nitrite reductase, copper-containing -
JM49_RS03785 830146..830445 + 300 WP_009051080.1 ArsR family transcriptional regulator -
JM49_RS03790 830503..831513 + 1011 WP_172666969.1 NAD(P)-dependent alcohol dehydrogenase -
JM49_RS03795 831538..831987 - 450 WP_007924098.1 DUF3828 domain-containing protein -
JM49_RS03800 832158..832457 + 300 WP_038575453.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JM49_RS03805 832454..832747 + 294 WP_038575454.1 putative addiction module antidote protein Antitoxin
JM49_RS03810 832880..833272 - 393 WP_023969315.1 hypothetical protein -
JM49_RS03820 833676..834811 + 1136 Protein_770 IS3 family transposase -
JM49_RS03825 834890..835777 - 888 WP_009051074.1 LysR family transcriptional regulator -
JM49_RS03830 835904..837094 + 1191 WP_038575459.1 serine hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 832158..837094 4936


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11193.96 Da        Isoelectric Point: 10.1833

>T48739 WP_038575453.1 NZ_CP009290:832158-832457 [Pseudomonas chlororaphis subsp. aurantiaca]
MIEIKQIATFMEWENRLKDPTARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQGRDIELAKYLARRWSRS

Download         Length: 300 bp

>T48739 NZ_CP009290:832158-832457 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGATCGAGATCAAACAGATCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATCCCACAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCTTGGCCAACGGCCTTGCCGGTGACGTGTCCCCGGTGGGCGAAGGCGTCAGCGAGCTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGCTCGGTTCGCAACTCGTCATCCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGGGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGTCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10440.97 Da        Isoelectric Point: 5.6558

>AT48739 WP_038575454.1 NZ_CP009290:832454-832747 [Pseudomonas chlororaphis subsp. aurantiaca]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAP

Download         Length: 294 bp

>AT48739 NZ_CP009290:832454-832747 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAGGCCATCGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTAGCGCGAGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGCGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGACATGACGGCGCGGGTGCACGGGGCGCCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References