Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1936671..1936815 Replicon chromosome
Accession NZ_CP009274
Organism Klebsiella variicola strain DX120E

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1936707..1936809 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1936671..1936815 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KR75_RS09175 1931801..1933861 + 2061 WP_012541258.1 oligopeptidase B -
KR75_RS09180 1933865..1934524 - 660 WP_012541259.1 exodeoxyribonuclease X -
KR75_RS09185 1934603..1934833 - 231 WP_012541260.1 DNA polymerase III subunit theta -
KR75_RS09190 1934947..1935321 + 375 WP_039103974.1 CopC domain-containing protein YobA -
KR75_RS09195 1935325..1936194 + 870 WP_039103972.1 copper homeostasis membrane protein CopD -
KR75_RS09200 1936211..1936549 + 339 WP_008804271.1 YebY family protein -
- 1936671..1936815 - 145 - - Antitoxin
- 1936707..1936809 + 103 - - Toxin
KR75_RS28905 1937194..1937337 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
KR75_RS09210 1937441..1938409 - 969 WP_162493241.1 VirK/YbjX family protein -
KR75_RS09215 1938566..1939219 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
KR75_RS09220 1939216..1939407 - 192 WP_002911395.1 YebW family protein -
KR75_RS09225 1939505..1939744 - 240 WP_002911393.1 YebV family protein -
KR75_RS09230 1939860..1941293 - 1434 WP_039103970.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T48713 NZ_CP009274:1936707-1936809 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT48713 NZ_CP009274:c1936815-1936671 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References