Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1917323..1917594 Replicon chromosome
Accession NZ_CP009273
Organism Escherichia coli BW25113

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1917361..1917464 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1917323..1917594 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BW25113_RS09615 (BW25113_1835) 1914480..1915919 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BW25113_RS09620 (BW25113_1836) 1916037..1916273 + 237 WP_001295499.1 DUF1480 family protein -
BW25113_RS09625 (BW25113_1837) 1916378..1916569 + 192 WP_000457842.1 YebW family protein -
BW25113_RS09630 (BW25113_1838) 1916570..1917226 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1917323..1917594 + 272 - - Antitoxin
- 1917361..1917464 - 104 - - Toxin
BW25113_RS09640 (BW25113_1839) 1917622..1917963 - 342 WP_000976476.1 YebY family protein -
BW25113_RS09645 (BW25113_1840) 1917976..1918848 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
BW25113_RS09650 (BW25113_1841) 1918852..1919226 - 375 WP_000168747.1 CopC domain-containing protein YobA -
BW25113_RS09655 (BW25113_1842) 1919365..1919595 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BW25113_RS09660 (BW25113_1843) 1919697..1920353 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
BW25113_RS09665 (BW25113_1844) 1920377..1921039 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T48684 NZ_CP009273:c1917464-1917361 [Escherichia coli BW25113]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT48684 NZ_CP009273:1917323-1917594 [Escherichia coli BW25113]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References