Detailed information of TA system TA048664

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 39368..39833
• Replicon: plasmid pOCN014
• Accession: NZ_CP009266
• Organism: Vibrio coralliilyticus strain OCN014

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JV59_RS26735
• Protein ID: WP_144397631.1
• Coordinates: 39654..39833 (+)
• Length: 60 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JV59_RS24750
• Protein ID: WP_040122439.1
• Coordinates: 39368..39559 (+)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JV59_RS24735	35594..37246	+	1653	WP_040122437.1	hypothetical protein	-
JV59_RS24740	37257..37962	+	706	Protein_43	OmpA family protein	-
JV59_RS24745	37959..39086	+	1128	WP_040122438.1	HNH endonuclease	-
JV59_RS24750	39368..39559	+	192	WP_040122439.1	hypothetical protein	Antitoxin
JV59_RS26735	39654..39833	+	180	WP_144397631.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JV59_RS24755	40059..41027	-	969	WP_040122440.1	hypothetical protein	-
JV59_RS26980	41159..41431	-	273	WP_144397619.1	hypothetical protein	-
JV59_RS24760	41496..43589	-	2094	WP_040122441.1	TonB-dependent siderophore receptor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..380781	380781

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-69)

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6795.04 Da
• Isoelectric Point: 9.2052

>T48664 WP_144397631.1 NZ_CP009266:39654-39833 [Vibrio coralliilyticus]
IIEVRVENLLEQPHMGVQRDGIRGRLLNTPKISMMVSYCESDTIHIMRVLHQKQKLPAA

Nucleotide

• Length: 180 bp

>T48664 NZ_CP009266:39654-39833 [Vibrio coralliilyticus]
ATAATTGAGGTAAGAGTGGAGAACCTTCTAGAGCAACCACATATGGGAGTCCAACGAGACGGAATTAGAGGGCGATTGCT
CAATACTCCTAAGATTTCAATGATGGTTTCCTACTGTGAAAGCGATACCATTCACATCATGCGTGTGCTGCACCAAAAAC
AAAAACTCCCAGCGGCTTGA

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7430.51 Da
• Isoelectric Point: 10.4888

>AT48664 WP_040122439.1 NZ_CP009266:39368-39559 [Vibrio coralliilyticus]
MKKRLAQQLADHKRKALFHDARLTEQVNLAFEKFDSKKVTFVDHESANSRMAEREAKICNRDK

Nucleotide

• Length: 192 bp

>AT48664 NZ_CP009266:39368-39559 [Vibrio coralliilyticus]
ATGAAGAAACGACTAGCTCAGCAACTGGCTGATCATAAGAGAAAGGCTTTATTTCACGACGCTCGGTTAACGGAACAAGT
TAACTTAGCTTTTGAGAAGTTTGACTCAAAAAAAGTCACTTTTGTCGACCACGAGTCAGCCAATTCTCGCATGGCGGAAC
GCGAAGCTAAAATCTGTAACCGAGACAAATGA