Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 343441..344000 Replicon chromosome
Accession NZ_CP009262
Organism Vibrio vulnificus strain 93U204

Toxin (Protein)


Gene name relE Uniprot ID A0A2S3R8G0
Locus tag VV93_RS16825 Protein ID WP_017420107.1
Coordinates 343722..344000 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3Q0L0M2
Locus tag VV93_RS16820 Protein ID WP_011082348.1
Coordinates 343441..343725 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VV93_RS16795 338983..340176 + 1194 WP_011082341.1 glycine C-acetyltransferase -
VV93_RS16800 340213..341238 + 1026 WP_197672410.1 L-threonine 3-dehydrogenase -
VV93_RS16805 341318..341818 - 501 WP_040110525.1 hypothetical protein -
VV93_RS16810 341895..342158 - 264 WP_040110526.1 hypothetical protein -
VV93_RS16815 342398..343207 - 810 WP_039452822.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
VV93_RS16820 343441..343725 + 285 WP_011082348.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
VV93_RS16825 343722..344000 + 279 WP_017420107.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
VV93_RS23805 344029..344118 - 90 WP_200877312.1 DUF3265 domain-containing protein -
VV93_RS16830 344124..345323 - 1200 WP_040110527.1 hypothetical protein -
VV93_RS16835 345485..345952 - 468 WP_040110528.1 hypothetical protein -
VV93_RS16840 347248..347763 - 516 WP_040110529.1 lipocalin family protein -
VV93_RS16845 347879..348502 - 624 WP_015727543.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-45)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10848.55 Da        Isoelectric Point: 4.2397

>T48663 WP_017420107.1 NZ_CP009262:343722-344000 [Vibrio vulnificus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGILGRLLIIPEISMVISYWVEGDIIRVM
RVLHQKQKFPTD

Download         Length: 279 bp

>T48663 NZ_CP009262:343722-344000 [Vibrio vulnificus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAATCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGGGATGGCA
TCCTCGGTCGATTACTCATTATTCCTGAGATTTCGATGGTTATCTCTTACTGGGTCGAGGGCGATATCATCCGAGTTATG
CGTGTCCTCCACCAGAAACAAAAATTCCCTACGGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11083.43 Da        Isoelectric Point: 9.2167

>AT48663 WP_011082348.1 NZ_CP009262:343441-343725 [Vibrio vulnificus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFIEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT48663 NZ_CP009262:343441-343725 [Vibrio vulnificus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTTAGTGACGCATGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTGTCTCACGATGCATGGCTAA
CTGAACAAGTAAATCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCATTGAGCACCAAACTGCTAAATCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S3R8G0

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q0L0M2

References