Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 692410..693038 Replicon chromosome
Accession NZ_CP009259
Organism Helicobacter pylori SS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HPYLSS1_RS03440 Protein ID WP_077232042.1
Coordinates 692410..692670 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HPYLSS1_RS03445 Protein ID WP_077232043.1
Coordinates 692748..693038 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HPYLSS1_RS03405 687761..688408 - 648 Protein_642 hypothetical protein -
HPYLSS1_RS03425 689124..691286 + 2163 WP_077232040.1 outer membrane beta-barrel protein -
HPYLSS1_RS03435 692052..692423 + 372 WP_077232041.1 hypothetical protein -
HPYLSS1_RS03440 692410..692670 + 261 WP_077232042.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
HPYLSS1_RS03445 692748..693038 + 291 WP_077232043.1 hypothetical protein Antitoxin
HPYLSS1_RS03450 693052..693213 + 162 WP_077232044.1 type II toxin-antitoxin system YafQ family toxin -
HPYLSS1_RS08095 693210..693409 + 200 Protein_648 virulence protein -
HPYLSS1_RS03460 693591..694115 - 525 WP_001135623.1 acyl-CoA thioesterase -
HPYLSS1_RS03465 694255..695109 + 855 WP_103153302.1 SDR family oxidoreductase -
HPYLSS1_RS03470 695102..696082 + 981 WP_077232045.1 iron ABC transporter permease -
HPYLSS1_RS03475 696082..696849 + 768 WP_000242355.1 ABC transporter ATP-binding protein -
HPYLSS1_RS03480 696930..698029 + 1100 Protein_653 glycosyltransferase family 8 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10250.18 Da        Isoelectric Point: 9.9512

>T48655 WP_077232042.1 NZ_CP009259:692410-692670 [Helicobacter pylori SS1]
MLKIRHHILFKKDFKKLVKNGFDDSVLNEVILRKKEPLDPQFQDHALKGKWKPFRECHIKADILLVYLVKDDELILLRLG
SHSELF

Download         Length: 261 bp

>T48655 NZ_CP009259:692410-692670 [Helicobacter pylori SS1]
ATGCTGAAAATTAGGCACCATATCCTTTTCAAAAAAGACTTTAAAAAACTCGTTAAAAACGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAAGAAAAAAAGAACCGCTAGATCCACAATTTCAAGATCATGCCTTAAAGGGAAAGTGGAAACCTT
TTAGGGAATGCCACATCAAAGCCGACATTTTGCTTGTGTATTTAGTGAAAGATGATGAACTGATTTTGTTAAGGTTAGGC
AGTCATAGCGAGTTGTTTTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11452.18 Da        Isoelectric Point: 10.2169

>AT48655 WP_077232043.1 NZ_CP009259:692748-693038 [Helicobacter pylori SS1]
MPNTTAKKDYTQYSERQLFNFLNSIKTKQKRALEKLKETQAQKQRIKKALQFKVLNLTENGYTIEEEREILARAKDTKNH
LCFKSVEDFKKHCENL

Download         Length: 291 bp

>AT48655 NZ_CP009259:692748-693038 [Helicobacter pylori SS1]
ATGCCTAACACCACCGCCAAAAAAGACTACACCCAATACAGCGAAAGACAGCTTTTTAACTTTTTAAATTCTATCAAGAC
CAAGCAAAAAAGAGCGTTAGAAAAATTGAAGGAAACCCAAGCTCAAAAACAAAGAATCAAAAAAGCGCTCCAATTTAAAG
TGCTAAACCTAACCGAAAATGGATACACCATAGAAGAAGAGCGAGAAATCTTAGCAAGGGCTAAAGATACCAAGAACCAC
CTTTGTTTTAAAAGCGTAGAGGATTTTAAAAAGCATTGTGAAAACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References