Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3793106..3793759 Replicon chromosome
Accession NZ_CP009256
Organism Acinetobacter baumannii strain AB31

Toxin (Protein)


Gene name cptA Uniprot ID A0A858S2K0
Locus tag IX88_RS17915 Protein ID WP_031999513.1
Coordinates 3793106..3793495 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag IX88_RS17920 Protein ID WP_001288210.1
Coordinates 3793502..3793759 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IX88_RS17900 3788224..3790419 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
IX88_RS17905 3790607..3791173 - 567 WP_000651536.1 rhombosortase -
IX88_RS17910 3791251..3792336 - 1086 WP_031999514.1 hypothetical protein -
IX88_RS17915 3793106..3793495 - 390 WP_031999513.1 membrane protein Toxin
IX88_RS17920 3793502..3793759 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
IX88_RS17925 3793947..3795119 + 1173 WP_017725189.1 acyl-CoA dehydrogenase family protein -
IX88_RS17930 3795168..3796658 - 1491 WP_000415132.1 NAD(P)/FAD-dependent oxidoreductase -
IX88_RS17935 3796840..3797217 - 378 WP_001216380.1 50S ribosomal protein L17 -
IX88_RS17940 3797236..3798243 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15598.85 Da        Isoelectric Point: 10.3889

>T48649 WP_031999513.1 NZ_CP009256:c3793495-3793106 [Acinetobacter baumannii]
MVNHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYQSQNTV
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T48649 NZ_CP009256:c3793495-3793106 [Acinetobacter baumannii]
TTGGTCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT48649 WP_001288210.1 NZ_CP009256:c3793759-3793502 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT48649 NZ_CP009256:c3793759-3793502 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A858S2K0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References