Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1516829..1517316 Replicon chromosome
Accession NZ_CP009227
Organism Treponema sp. OMZ 838 strain OMZ 838 (ATCC 700772)

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QI63_RS06785 Protein ID WP_044014984.1
Coordinates 1516829..1517095 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QI63_RS06790 Protein ID WP_044014985.1
Coordinates 1517095..1517316 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QI63_RS06765 1512407..1513969 - 1563 WP_044014981.1 citrate lyase subunit alpha -
QI63_RS06770 1513972..1514880 - 909 WP_044014982.1 HpcH/HpaI aldolase/citrate lyase family protein -
QI63_RS06775 1514908..1515195 - 288 WP_006188864.1 citrate lyase acyl carrier protein -
QI63_RS06780 1515479..1516522 + 1044 WP_044014983.1 [citrate (pro-3S)-lyase] ligase -
QI63_RS06785 1516829..1517095 - 267 WP_044014984.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QI63_RS06790 1517095..1517316 - 222 WP_044014985.1 hypothetical protein Antitoxin
QI63_RS06795 1517447..1517866 - 420 WP_044014986.1 PIN domain-containing protein -
QI63_RS06800 1517859..1518098 - 240 WP_044014987.1 hypothetical protein -
QI63_RS06805 1518364..1519770 + 1407 WP_200877783.1 ribosome biogenesis GTPase Der -
QI63_RS06810 1519767..1520126 + 360 WP_044017151.1 MerR family transcriptional regulator -
QI63_RS06815 1520172..1520828 + 657 WP_044014993.1 hypothetical protein -
QI63_RS06820 1520849..1521637 + 789 WP_044014995.1 RNA polymerase sigma factor WhiG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10359.84 Da        Isoelectric Point: 9.9931

>T48565 WP_044014984.1 NZ_CP009227:c1517095-1516829 [Treponema sp. OMZ 838]
MYRVETTARFDKEFKKLDKYTQRMIAAWIDKNLEGSENPRVHGKGLTANRSGQWRYRIGDYRLICAIQDNELVILALTVG
HRRAVYDQ

Download         Length: 267 bp

>T48565 NZ_CP009227:c1517095-1516829 [Treponema sp. OMZ 838]
ATGTACAGGGTTGAAACGACTGCTCGATTTGATAAAGAATTTAAAAAACTGGATAAATATACGCAACGCATGATAGCTGC
ATGGATTGATAAGAACCTTGAAGGCTCGGAAAATCCGCGCGTACATGGAAAAGGTCTCACAGCAAATAGAAGCGGACAGT
GGCGATACAGAATAGGAGATTATCGGCTGATATGTGCAATACAGGACAATGAACTTGTTATTCTTGCTCTAACTGTCGGC
CATCGAAGGGCGGTTTACGATCAGTAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8205.24 Da        Isoelectric Point: 4.8223

>AT48565 WP_044014985.1 NZ_CP009227:c1517316-1517095 [Treponema sp. OMZ 838]
MAFSIRLTEAERAIANSYAKLHSVSLGEAFKNALFEKIEDEYDITVAAEAYQEYESAGKKSRPFSELKKELGL

Download         Length: 222 bp

>AT48565 NZ_CP009227:c1517316-1517095 [Treponema sp. OMZ 838]
ATGGCGTTTTCAATACGGTTGACAGAAGCAGAAAGAGCTATTGCGAATAGCTATGCAAAACTGCATTCGGTATCATTGGG
CGAAGCTTTTAAGAATGCATTGTTTGAAAAAATTGAAGATGAATATGATATTACTGTTGCTGCGGAGGCATATCAAGAAT
ATGAGAGTGCCGGGAAAAAAAGCCGCCCATTTTCTGAACTCAAGAAAGAGTTAGGTTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References