Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 4042491..4043131 Replicon chromosome
Accession NZ_CP009125
Organism Pectobacterium atrosepticum strain 21A

Toxin (Protein)


Gene name vagD Uniprot ID Q6D0W3
Locus tag GZ59_RS17880 Protein ID WP_011095186.1
Coordinates 4042491..4042907 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID Q6D0W2
Locus tag GZ59_RS17885 Protein ID WP_011095187.1
Coordinates 4042904..4043131 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
- 4042491..4042907 - 417 - - Toxin
- 4042904..4043131 - 228 - - Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-129)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15299.98 Da        Isoelectric Point: 8.7720

>T48437 WP_011095186.1 NZ_CP009125:c4042907-4042491 [Pectobacterium atrosepticum]
VSRLFMLDTNICSFIMREHPSAVIEKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMLLVDAFCRRLDAILPWDSA
AVDATTKIKIALAAAVTPIGPNDTAIAGHAISAKAILVTNNLREFERVPELILEDWVK

Download         Length: 417 bp

>T48437 NZ_CP009125:c4042907-4042491 [Pectobacterium atrosepticum]
GTGAGCCGTTTGTTCATGCTTGATACTAATATCTGTTCTTTCATTATGCGTGAACACCCGTCTGCGGTGATTGAAAAGTT
GCAGCAATGCACACTGCGACGAGATCGAATCGTGGTATCAGCTATCACGTACGCTGAAATGCGTTTTGGGGCGGTTGGCA
AAAAAGCTTCGCCGCGCCATATGCTGCTGGTTGATGCTTTCTGCCGCCGACTTGATGCGATATTACCTTGGGATAGCGCA
GCGGTAGACGCCACCACAAAAATTAAAATTGCACTAGCTGCAGCTGTCACACCTATTGGTCCAAACGATACGGCCATCGC
TGGTCATGCTATCAGCGCTAAGGCCATACTAGTCACCAATAATCTGAGAGAATTTGAGCGAGTACCGGAACTGATACTGG
AAGATTGGGTTAAATAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8894.05 Da        Isoelectric Point: 4.5216

>AT48437 WP_011095187.1 NZ_CP009125:c4043131-4042904 [Pectobacterium atrosepticum]
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWHSFLQEERADADFMTERQDVVEEGRFEL

Download         Length: 228 bp

>AT48437 NZ_CP009125:c4043131-4042904 [Pectobacterium atrosepticum]
ATGCGTATTGTCTCAGTATTTAAAAATGGTAATAACCGTGCTATTCGCTTGCCGCGTGATATGGACTTTGAAGGCGTCAA
TGAACTGGAGATCGTGCGTGAAGGGGATACCATCATGTTGCGCCCAGTCAAACCCAATTGGCATTCTTTTCTGCAAGAAG
AGCGTGCTGACGCAGACTTTATGACAGAACGTCAGGATGTAGTCGAAGAGGGGAGATTCGAACTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6D0W3

Antitoxin

Source ID Structure
AlphaFold DB A0A0J5XN10

References