Detailed information of TA system TA048436

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1944452..1945362
• Replicon: chromosome
• Accession: NZ_CP009125
• Organism: Pectobacterium atrosepticum strain 21A

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: GZ59_RS08460
• Protein ID: WP_039291191.1
• Coordinates: 1944892..1945362 (+)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: GZ59_RS08455
• Protein ID: WP_039291190.1
• Coordinates: 1944452..1944895 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GZ59_RS08435	1939629..1940618	+	990	WP_039291185.1	iron ABC transporter permease	-
GZ59_RS08440	1940611..1941642	+	1032	WP_039291186.1	iron ABC transporter permease	-
GZ59_RS08445	1941670..1942509	+	840	WP_199559463.1	ABC transporter ATP-binding protein	-
GZ59_RS08450	1942787..1944238	+	1452	WP_039291188.1	ATP-dependent RNA helicase RhlE	-
GZ59_RS23470	1944279..1944392	-	114	Protein_1661	EamA family transporter	-
GZ59_RS08455	1944452..1944895	+	444	WP_039291190.1	DUF2384 domain-containing protein	Antitoxin
GZ59_RS08460	1944892..1945362	+	471	WP_039291191.1	RES family NAD+ phosphorylase	Toxin
GZ59_RS08465	1945419..1946648	-	1230	WP_039291193.1	peptidase T	-
GZ59_RS08470	1946789..1948384	+	1596	WP_039291195.1	ABC transporter substrate-binding protein	-
GZ59_RS08475	1948431..1949102	-	672	WP_039291197.1	epoxyqueuosine reductase QueH	-
GZ59_RS08480	1949346..1950278	+	933	WP_039291199.1	tRNA dihydrouridine(16) synthase DusC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-145)

Antitoxin

• Antitoxin Xre (16-147)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 17637.08 Da
• Isoelectric Point: 4.4093

>T48436 WP_039291191.1 NZ_CP009125:1944892-1945362 [Pectobacterium atrosepticum]
MILYRLTKTKYLSTAWTGYGAKEAGGRWNSIGTSMVYVSETASLAMLETLVHLHAAQILDYYTLMRIDVPEDQIQSADMD
ELPDNWAAEEAPPDLAVYGDAWIFTKGSIALRVPSALSPVEYNYLLNPEHPDFYGIIQMAEIIPFQFDSRLKPDRK

Nucleotide

• Length: 471 bp

>T48436 NZ_CP009125:1944892-1945362 [Pectobacterium atrosepticum]
TTGATTCTCTATCGGCTTACAAAGACAAAGTATCTTTCTACAGCCTGGACGGGATACGGAGCAAAAGAGGCTGGAGGCCG
CTGGAATAGTATTGGCACCTCGATGGTTTATGTATCAGAAACCGCATCGCTTGCCATGCTGGAGACGCTGGTACATCTGC
ATGCAGCGCAGATCCTGGATTATTACACGCTAATGCGTATCGATGTGCCTGAGGATCAGATTCAGAGTGCCGATATGGAC
GAATTGCCAGACAACTGGGCTGCTGAAGAAGCGCCGCCAGATCTGGCTGTATACGGTGATGCATGGATCTTTACCAAAGG
TTCGATAGCGTTGCGAGTCCCCAGCGCCCTATCGCCTGTAGAGTATAACTACCTGTTAAACCCTGAACACCCAGATTTCT
ACGGGATCATTCAGATGGCAGAGATTATACCGTTCCAGTTTGATAGCCGGCTAAAGCCCGATCGTAAATAA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16345.69 Da
• Isoelectric Point: 9.5903

>AT48436 WP_039291190.1 NZ_CP009125:1944452-1944895 [Pectobacterium atrosepticum]
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLEGKVANLIADWAKITQNDLRKMSGIPSTTFSRSVKARFSADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALGGKVPAELMVSETGAYEVMKLLTRLEHGVYS

Nucleotide

• Length: 444 bp

>AT48436 NZ_CP009125:1944452-1944895 [Pectobacterium atrosepticum]
ATGAAAACATTTAGCTTATCCACGACTCAGACCAGGCCGCCCCGTTTATGGCAGGTGGCCGGATTAAACAATTCTGATGG
TGTGGCGCTTCTGGGACAGATTAACGAAGGCCTTGAGGGCAAGGTTGCTAACCTTATCGCTGACTGGGCGAAGATAACGC
AAAACGACCTGCGTAAAATGTCCGGCATTCCGTCAACGACGTTTAGCCGCAGCGTCAAAGCGCGATTTAGCGCCGATCAA
AGTGAACGGCTGGTGCGTATCATCCGTGTCATTGATCGGGCGGTAGAACTGTTCGAAGGTGATAAGGACGAGGCTCAAAA
ATGGTTGAATGAGCCAAACCGAGCGCTTGGCGGGAAAGTGCCAGCAGAACTGATGGTATCCGAAACCGGGGCTTACGAAG
TCATGAAATTGCTCACGCGCCTGGAACATGGTGTGTACTCTTGA