48169

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 630277..632006 Replicon chromosome
Accession NZ_CP009048
Organism Pseudomonas alkylphenolica strain KL28

Toxin (Protein)


Gene name pmenT Uniprot ID A0A077F320
Locus tag PSAKL28_RS02955 Protein ID WP_038606318.1
Coordinates 631362..632006 (-) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID A0A077F2V3
Locus tag PSAKL28_RS02950 Protein ID WP_038606315.1
Coordinates 630277..631365 (-) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSAKL28_RS02930 625616..626707 - 1092 WP_157686995.1 hypothetical protein -
PSAKL28_RS02935 626807..627754 - 948 WP_038606310.1 LysR family transcriptional regulator -
PSAKL28_RS02940 627837..629162 + 1326 WP_051939138.1 MFS transporter -
PSAKL28_RS02945 629195..630094 + 900 WP_038606313.1 carbon-nitrogen hydrolase family protein -
PSAKL28_RS02950 630277..631365 - 1089 WP_038606315.1 macro domain-containing protein Antitoxin
PSAKL28_RS02955 631362..632006 - 645 WP_038606318.1 DUF4433 domain-containing protein Toxin
PSAKL28_RS02960 632007..632576 - 570 WP_038606320.1 DUF4433 domain-containing protein -
PSAKL28_RS02965 632796..633707 - 912 WP_038606323.1 restriction endonuclease -
PSAKL28_RS02970 634205..634477 + 273 WP_010487122.1 CopG family ribbon-helix-helix protein -
PSAKL28_RS26660 634465..634758 + 294 WP_075226426.1 type II toxin-antitoxin system RelE/ParE family toxin -
PSAKL28_RS02975 635138..636109 + 972 WP_038616202.1 inovirus-type Gp2 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24950.51 Da        Isoelectric Point: 7.1704

>T48169 WP_038606318.1 NZ_CP009048:c632006-631362 [Pseudomonas alkylphenolica]
MIYSRLNPEKALIWRIVHRDNLPWILENGLHCANSGVQSPQYVNIGNADLIDKRRSRRVPIAPGGVLADYVPFYFTPFSV
MMKNIHSGWSVQQRSNDEIVILVSSLYRVEQLGLPFVYTNAHAYPDWTDYYSDLANLDQIDWPIIQRRDFKREPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYTDAMKERIERDVANQGLTLPVHARPGWYFQ

Download         Length: 645 bp

>T48169 NZ_CP009048:c632006-631362 [Pseudomonas alkylphenolica]
ATGATCTACAGCAGACTGAATCCAGAGAAGGCTCTGATTTGGCGTATCGTCCACCGCGACAACCTGCCTTGGATTCTGGA
AAACGGTCTGCATTGCGCAAACTCAGGTGTGCAGTCGCCCCAGTATGTAAACATCGGCAACGCTGACCTGATCGACAAGC
GCAGATCAAGGCGCGTCCCGATAGCGCCAGGAGGGGTACTAGCCGACTACGTGCCCTTCTATTTCACCCCCTTCTCTGTG
ATGATGAAAAACATTCATTCTGGGTGGAGTGTTCAGCAGCGTAGCAACGACGAGATCGTGATACTGGTCTCTAGCCTGTA
CCGCGTTGAACAGCTGGGCCTACCGTTTGTCTACACAAACGCACACGCCTATCCGGATTGGACAGACTATTACAGCGACT
TGGCGAATCTCGACCAGATCGATTGGCCTATCATCCAAAGACGCGACTTCAAGCGCGAACCTGACGACCCTCGGAAGATG
GAGCGTTATCAGGCCGAAGCGCTGATTCACCATCACTTACCGATTACAGGACTCCTGGGCATCATGTGCTACACCGATGC
GATGAAAGAACGCATAGAACGAGACGTTGCCAACCAAGGCTTGACGTTGCCTGTTCATGCGCGTCCGGGATGGTATTTCC
AATGA

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40730.78 Da        Isoelectric Point: 7.4126

>AT48169 WP_038606315.1 NZ_CP009048:c631365-630277 [Pseudomonas alkylphenolica]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAENYRLYSAACKAGEVETGKVHVTAVNELEGPRWIVNFPTK
RHWRSPSQMAWVTEGLHDLRRFLIENQVKSVAVPPLGAGNGGLKWPEVREQIVAVLSDLDVDVLVFEPSNQYLNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKLPDTKNPLNLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAGISDVIWFDEDRKAYLQTYLKTEAKEYSQALERTAKLIDGFESPFGMELLATVDWLLSQEGVSPSVPAVREA
LRHWDGGAGAAARKSRLFDDQALDIALKRLTSSSFRPEVTTC

Download         Length: 1089 bp

>AT48169 NZ_CP009048:c631365-630277 [Pseudomonas alkylphenolica]
ATGATCAGATTTACCCAAGGCAACCTTCTGGAAGCCAAGACCGAAGCCCTCGTCAACACGGTGAATACCGTTGGCGTAAT
GGGTAAAGGCATCGCGCTGATGTTCAAGGAGCGTTTCGCGGAAAATTATCGCCTGTACTCGGCTGCCTGCAAGGCTGGCG
AAGTGGAAACAGGCAAAGTTCACGTAACTGCAGTCAACGAGCTGGAAGGTCCTCGCTGGATCGTAAACTTCCCCACCAAA
CGTCACTGGCGATCCCCTTCGCAGATGGCATGGGTGACGGAAGGTCTGCATGATCTACGTCGGTTTTTGATTGAAAATCA
GGTCAAGTCCGTGGCTGTTCCACCGCTGGGCGCCGGTAACGGCGGTCTGAAATGGCCGGAAGTCCGCGAACAGATTGTTG
CCGTATTGAGTGACTTGGATGTGGATGTCTTGGTCTTTGAACCTTCCAACCAGTATCTGAATGTCGCTAAACGTAGCGGA
GTGGAAAAACTCACGCCTGCTCGCGCGCTCATCGCCGAACTGGTTCGACGCTATTGGGTTTTAGGCATGGAATGCAGCCT
GCTTGAGATTCAAAAGCTGGCCTGGTTCCTTGAGCGCGCCATAGAAAAGCTGCCAGATACCAAGAACCCTCTGAACCTTA
AGTTTGTAGCTCATAAATACGGGCCGTACGCCAACCGATTGGAGCATCTGCTCAACAACTTGGATGGCAGCTATTTGCAT
TGCGACAAACGTATCAGTGATGCCGGTATAAGTGATGTGATCTGGTTTGACGAAGACCGCAAAGCCTATCTACAAACCTA
TCTCAAAACAGAGGCCAAGGAGTATTCCCAAGCCCTGGAGCGCACCGCCAAGTTGATCGATGGCTTTGAGTCACCCTTTG
GTATGGAGTTGTTGGCAACAGTTGATTGGTTGCTGAGTCAGGAAGGGGTTTCCCCGAGCGTTCCCGCCGTACGTGAAGCG
TTAAGGCATTGGGATGGTGGTGCAGGCGCTGCTGCTCGCAAAAGCAGACTATTCGATGATCAGGCGCTTGATATTGCGCT
CAAACGTCTCACTTCCAGTAGTTTCAGACCTGAAGTGACTACCTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A077F320

Antitoxin

Source ID Structure
AlphaFold DB A0A077F2V3

References