48140

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 363861..364222 Replicon chromosome
Accession NZ_CP009040
Organism Xanthomonas citri pv. citri strain AW16

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD06_RS01835 Protein ID WP_005914328.1
Coordinates 364088..364222 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD06_RS01830 Protein ID WP_003486606.1
Coordinates 363861..364013 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD06_RS01800 358961..359644 - 684 WP_011052674.1 dTMP kinase -
AMD06_RS01805 360082..360624 - 543 WP_003486615.1 GTPase -
AMD06_RS01810 360621..361538 - 918 WP_011052673.1 hypothetical protein -
AMD06_RS01815 361635..361994 - 360 WP_003486613.1 hypothetical protein -
AMD06_RS01820 362058..362510 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD06_RS01825 362831..363754 + 924 WP_005927745.1 arginase -
AMD06_RS01830 363861..364013 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD06_RS01835 364088..364222 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD06_RS01840 364449..364658 + 210 WP_003486601.1 CsbD family protein -
AMD06_RS01845 364839..366128 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD06_RS01850 366167..367201 + 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD06_RS01855 367393..369084 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48140 WP_005914328.1 NZ_CP009040:364088-364222 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48140 NZ_CP009040:364088-364222 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48140 WP_003486606.1 NZ_CP009040:363861-364013 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48140 NZ_CP009040:363861-364013 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References