Detailed information of TA system TA048136

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 2701679..2702312
• Replicon: chromosome
• Accession: NZ_CP009037
• Organism: Xanthomonas citri pv. citri strain AW15

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: AMD07_RS12030
• Protein ID: WP_015463212.1
• Coordinates: 2701679..2702092 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: M4TWF0
• Locus tag: AMD07_RS12035
• Protein ID: WP_015463213.1
• Coordinates: 2702079..2702312 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AMD07_RS12020	2697371..2699551	+	2181	WP_011051394.1	TonB-dependent siderophore receptor	-
AMD07_RS12025	2699760..2701274	+	1515	WP_015463210.1	conjugal transfer protein TraG N-terminal domain-containing protein	-
AMD07_RS24350	2701290..2701652	-	363	WP_015463211.1	DUF3742 family protein	-
AMD07_RS12030	2701679..2702092	-	414	WP_015463212.1	PIN domain-containing protein	Toxin
AMD07_RS12035	2702079..2702312	-	234	WP_015463213.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
AMD07_RS12040	2702594..2703601	+	1008	WP_199822817.1	DUF4917 family protein	-
AMD07_RS12045	2703734..2704132	-	399	WP_099521978.1	hypothetical protein	-
AMD07_RS12050	2704584..2705159	+	576	WP_011051400.1	sigma-70 family RNA polymerase sigma factor	-
AMD07_RS12055	2705140..2706189	+	1050	WP_015472205.1	FecR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-119)

Antitoxin

• SpoVT-AbrB domain (5-45)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15221.65 Da
• Isoelectric Point: 6.3225

>T48136 WP_015463212.1 NZ_CP009037:c2702092-2701679 [Xanthomonas citri pv. citri]
MAAGKGKVFLDSNVVLYLLSEDAVKADGAEALLQRRPVISVQVLNEVTHVCVRKLKMGWDEVGQFLALVRSFCKIVPLTV
DVHDRARQLAERHQLSFYDACIVAAAAIEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Nucleotide

• Length: 414 bp

>T48136 NZ_CP009037:c2702092-2701679 [Xanthomonas citri pv. citri]
ATGGCCGCGGGTAAGGGCAAAGTGTTTCTCGACAGCAACGTGGTGCTCTACCTGCTGTCGGAGGATGCGGTGAAGGCGGA
CGGCGCGGAGGCATTGCTGCAGCGCAGGCCCGTCATCAGTGTGCAGGTGCTCAATGAAGTGACCCACGTCTGCGTTCGCA
AGCTCAAGATGGGCTGGGACGAAGTCGGGCAGTTCCTTGCGTTGGTGCGATCGTTCTGCAAGATAGTGCCTCTGACGGTC
GATGTTCACGACCGTGCGCGCCAGCTGGCGGAGCGGCACCAATTGTCGTTCTACGACGCGTGCATCGTGGCGGCGGCCGC
CATCGAAGGGTGCCAGACCCTCTACTCCGAAGACATGCACCACGGCCTCATCATCGAAGAGAGCCTGTCGATTCGGAACC
CGTTCAACGTCTGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8663.97 Da
• Isoelectric Point: 8.7848

>AT48136 WP_015463213.1 NZ_CP009037:c2702312-2702079 [Xanthomonas citri pv. citri]
MQVAKWGNSLAVRLPSSLVEALELREGDDIEIVVDDPRLFAVRKKPGPEAMLERLRAFRGKLPADFKFNRDEANGRG

Nucleotide

• Length: 234 bp

>AT48136 NZ_CP009037:c2702312-2702079 [Xanthomonas citri pv. citri]
ATGCAAGTCGCGAAGTGGGGTAACAGCCTGGCGGTGCGCCTGCCGTCCAGTCTGGTGGAAGCGCTGGAACTGCGCGAGGG
CGACGACATCGAGATCGTCGTCGATGATCCGCGATTGTTCGCGGTGCGCAAGAAGCCGGGTCCGGAGGCCATGTTGGAGC
GGCTGCGTGCCTTCCGGGGCAAGTTGCCCGCAGATTTCAAGTTCAACCGGGACGAGGCCAATGGCCGCGGGTAA

Structures

Antitoxin

• AlphaFold DB: M4TWF0