48133

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 363911..364272 Replicon chromosome
Accession NZ_CP009037
Organism Xanthomonas citri pv. citri strain AW15

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD07_RS01835 Protein ID WP_005914328.1
Coordinates 364138..364272 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD07_RS01830 Protein ID WP_003486606.1
Coordinates 363911..364063 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD07_RS01800 359011..359694 - 684 WP_011052674.1 dTMP kinase -
AMD07_RS01805 360132..360674 - 543 WP_003486615.1 GTPase -
AMD07_RS01810 360671..361588 - 918 WP_011052673.1 hypothetical protein -
AMD07_RS01815 361685..362044 - 360 WP_003486613.1 hypothetical protein -
AMD07_RS01820 362108..362560 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD07_RS01825 362881..363804 + 924 WP_005927745.1 arginase -
AMD07_RS01830 363911..364063 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD07_RS01835 364138..364272 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD07_RS01840 364499..364708 + 210 WP_003486601.1 CsbD family protein -
AMD07_RS01845 364889..366178 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD07_RS01850 366217..367251 + 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD07_RS01855 367443..369134 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48133 WP_005914328.1 NZ_CP009037:364138-364272 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48133 NZ_CP009037:364138-364272 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48133 WP_003486606.1 NZ_CP009037:363911-364063 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48133 NZ_CP009037:363911-364063 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References