48126

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 363910..364271 Replicon chromosome
Accession NZ_CP009034
Organism Xanthomonas citri pv. citri strain AW14

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD08_RS01835 Protein ID WP_005914328.1
Coordinates 364137..364271 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD08_RS01830 Protein ID WP_003486606.1
Coordinates 363910..364062 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD08_RS01800 359010..359693 - 684 WP_011052674.1 dTMP kinase -
AMD08_RS01805 360131..360673 - 543 WP_003486615.1 GTPase -
AMD08_RS01810 360670..361587 - 918 WP_011052673.1 hypothetical protein -
AMD08_RS01815 361684..362043 - 360 WP_003486613.1 hypothetical protein -
AMD08_RS01820 362107..362559 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD08_RS01825 362880..363803 + 924 WP_005927745.1 arginase -
AMD08_RS01830 363910..364062 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD08_RS01835 364137..364271 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD08_RS01840 364498..364707 + 210 WP_003486601.1 CsbD family protein -
AMD08_RS01845 364888..366177 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD08_RS01850 366216..367250 + 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD08_RS01855 367442..369133 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48126 WP_005914328.1 NZ_CP009034:364137-364271 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48126 NZ_CP009034:364137-364271 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48126 WP_003486606.1 NZ_CP009034:363910-364062 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48126 NZ_CP009034:363910-364062 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References