48091

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4650169..4650530 Replicon chromosome
Accession NZ_CP009019
Organism Xanthomonas citri pv. citri strain GD2

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD23_RS20505 Protein ID WP_005914328.1
Coordinates 4650169..4650303 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD23_RS20510 Protein ID WP_003486606.1
Coordinates 4650378..4650530 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD23_RS20485 4645307..4646998 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
AMD23_RS20490 4647190..4648224 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD23_RS20495 4648263..4649552 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD23_RS20500 4649733..4649942 - 210 WP_003486601.1 CsbD family protein -
AMD23_RS20505 4650169..4650303 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD23_RS20510 4650378..4650530 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD23_RS20515 4650637..4651560 - 924 WP_005927745.1 arginase -
AMD23_RS20520 4651881..4652333 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD23_RS20525 4652397..4652756 + 360 WP_003486613.1 hypothetical protein -
AMD23_RS20530 4652853..4653770 + 918 WP_011052673.1 hypothetical protein -
AMD23_RS20535 4653767..4654309 + 543 WP_003486615.1 GTPase -
AMD23_RS20540 4654747..4655430 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48091 WP_005914328.1 NZ_CP009019:c4650303-4650169 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48091 NZ_CP009019:c4650303-4650169 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48091 WP_003486606.1 NZ_CP009019:c4650530-4650378 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48091 NZ_CP009019:c4650530-4650378 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References