48083

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4650171..4650532 Replicon chromosome
Accession NZ_CP009016
Organism Xanthomonas citri pv. citri strain GD3

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD22_RS20490 Protein ID WP_005914328.1
Coordinates 4650171..4650305 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD22_RS20495 Protein ID WP_003486606.1
Coordinates 4650380..4650532 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD22_RS20470 4645309..4647000 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
AMD22_RS20475 4647192..4648226 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD22_RS20480 4648265..4649554 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD22_RS20485 4649735..4649944 - 210 WP_003486601.1 CsbD family protein -
AMD22_RS20490 4650171..4650305 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD22_RS20495 4650380..4650532 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD22_RS20500 4650639..4651562 - 924 WP_005927745.1 arginase -
AMD22_RS20505 4651883..4652335 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD22_RS20510 4652399..4652758 + 360 WP_003486613.1 hypothetical protein -
AMD22_RS20515 4652855..4653772 + 918 WP_011052673.1 hypothetical protein -
AMD22_RS20520 4653769..4654311 + 543 WP_003486615.1 GTPase -
AMD22_RS20525 4654749..4655432 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48083 WP_005914328.1 NZ_CP009016:c4650305-4650171 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48083 NZ_CP009016:c4650305-4650171 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48083 WP_003486606.1 NZ_CP009016:c4650532-4650380 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48083 NZ_CP009016:c4650532-4650380 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References