Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4649862..4650223 Replicon chromosome
Accession NZ_CP009010
Organism Xanthomonas citri pv. citri strain JX5

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD20_RS20500 Protein ID WP_005914328.1
Coordinates 4649862..4649996 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD20_RS20505 Protein ID WP_003486606.1
Coordinates 4650071..4650223 (-) Length 51 a.a.

Genomic Context

AMD20_RS20515AMD20_RS20520AMD20_RS20525AMD20_RS20530AMD20_RS20535AMD20_RS20480AMD20_RS20485AMD20_RS20490AMD20_RS20495AMD20_RS20500AMD20_RS20505AMD20_RS20510
Location: 4651574..4652026 (453 bp)
Type: Others
Protein ID: WP_003486611.1
Location: 4652090..4652449 (360 bp)
Type: Others
Protein ID: WP_003486613.1
Location: 4652546..4653463 (918 bp)
Type: Others
Protein ID: WP_011052673.1
Location: 4653460..4654002 (543 bp)
Type: Others
Protein ID: WP_003486615.1
Location: 4654440..4655123 (684 bp)
Type: Others
Protein ID: WP_011052674.1
Location: 4645000..4646691 (1692 bp)
Type: Others
Protein ID: WP_015471463.1
Location: 4646883..4647917 (1035 bp)
Type: Others
Protein ID: WP_011052671.1
Location: 4647956..4649245 (1290 bp)
Type: Others
Protein ID: WP_015463705.1
Location: 4649426..4649635 (210 bp)
Type: Others
Protein ID: WP_003486601.1
Location: 4649862..4649996 (135 bp)
Type: Toxin
Protein ID: WP_005914328.1
Location: 4650071..4650223 (153 bp)
Type: Antitoxin
Protein ID: WP_003486606.1
Location: 4650330..4651253 (924 bp)
Type: Others
Protein ID: WP_005927745.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AMD20_RS204804645000..4646691-1692WP_015471463.1M20/M25/M40 family metallo-hydrolase-
AMD20_RS204854646883..4647917-1035WP_011052671.1MBL fold metallo-hydrolase-
AMD20_RS204904647956..4649245-1290WP_015463705.1tryptophan--tRNA ligase-
AMD20_RS204954649426..4649635-210WP_003486601.1CsbD family protein-
AMD20_RS205004649862..4649996-135WP_005914328.1entericidin A/B family lipoproteinToxin
AMD20_RS205054650071..4650223-153WP_003486606.1entericidin A/B family lipoproteinAntitoxin
AMD20_RS205104650330..4651253-924WP_005927745.1arginase-
AMD20_RS205154651574..4652026+453WP_003486611.1roadblock/LC7 domain-containing protein-
AMD20_RS205204652090..4652449+360WP_003486613.1hypothetical protein-
AMD20_RS205254652546..4653463+918WP_011052673.1hypothetical protein-
AMD20_RS205304653460..4654002+543WP_003486615.1GTPase-
AMD20_RS205354654440..4655123+684WP_011052674.1dTMP kinase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48067 WP_005914328.1 NZ_CP009010:c4649996-4649862 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48067 NZ_CP009010:c4649996-4649862 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48067 WP_003486606.1 NZ_CP009010:c4650223-4650071 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48067 NZ_CP009010:c4650223-4650071 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A3G2W7U6

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A828YLX6

References