48067

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4649862..4650223 Replicon chromosome
Accession NZ_CP009010
Organism Xanthomonas citri pv. citri strain JX5

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD20_RS20500 Protein ID WP_005914328.1
Coordinates 4649862..4649996 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD20_RS20505 Protein ID WP_003486606.1
Coordinates 4650071..4650223 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD20_RS20480 4645000..4646691 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
AMD20_RS20485 4646883..4647917 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD20_RS20490 4647956..4649245 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD20_RS20495 4649426..4649635 - 210 WP_003486601.1 CsbD family protein -
AMD20_RS20500 4649862..4649996 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD20_RS20505 4650071..4650223 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD20_RS20510 4650330..4651253 - 924 WP_005927745.1 arginase -
AMD20_RS20515 4651574..4652026 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD20_RS20520 4652090..4652449 + 360 WP_003486613.1 hypothetical protein -
AMD20_RS20525 4652546..4653463 + 918 WP_011052673.1 hypothetical protein -
AMD20_RS20530 4653460..4654002 + 543 WP_003486615.1 GTPase -
AMD20_RS20535 4654440..4655123 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48067 WP_005914328.1 NZ_CP009010:c4649996-4649862 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48067 NZ_CP009010:c4649996-4649862 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48067 WP_003486606.1 NZ_CP009010:c4650223-4650071 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48067 NZ_CP009010:c4650223-4650071 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References