Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4700595..4700956 Replicon chromosome
Accession NZ_CP009007
Organism Xanthomonas citri pv. citri strain MF20

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD10_RS20635 Protein ID WP_005914328.1
Coordinates 4700595..4700729 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD10_RS20640 Protein ID WP_003486606.1
Coordinates 4700804..4700956 (-) Length 51 a.a.

Genomic Context

AMD10_RS20650AMD10_RS20655AMD10_RS20660AMD10_RS20665AMD10_RS20670AMD10_RS20615AMD10_RS20620AMD10_RS20625AMD10_RS20630AMD10_RS20635AMD10_RS20640AMD10_RS20645
Location: 4702307..4702759 (453 bp)
Type: Others
Protein ID: WP_003486611.1
Location: 4702823..4703182 (360 bp)
Type: Others
Protein ID: WP_003486613.1
Location: 4703279..4704196 (918 bp)
Type: Others
Protein ID: WP_011052673.1
Location: 4704193..4704735 (543 bp)
Type: Others
Protein ID: WP_003486615.1
Location: 4705173..4705856 (684 bp)
Type: Others
Protein ID: WP_011052674.1
Location: 4695733..4697424 (1692 bp)
Type: Others
Protein ID: WP_015471463.1
Location: 4697616..4698650 (1035 bp)
Type: Others
Protein ID: WP_011052671.1
Location: 4698689..4699978 (1290 bp)
Type: Others
Protein ID: WP_015463705.1
Location: 4700159..4700368 (210 bp)
Type: Others
Protein ID: WP_003486601.1
Location: 4700595..4700729 (135 bp)
Type: Toxin
Protein ID: WP_005914328.1
Location: 4700804..4700956 (153 bp)
Type: Antitoxin
Protein ID: WP_003486606.1
Location: 4701063..4701986 (924 bp)
Type: Others
Protein ID: WP_005927745.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AMD10_RS206154695733..4697424-1692WP_015471463.1M20/M25/M40 family metallo-hydrolase-
AMD10_RS206204697616..4698650-1035WP_011052671.1MBL fold metallo-hydrolase-
AMD10_RS206254698689..4699978-1290WP_015463705.1tryptophan--tRNA ligase-
AMD10_RS206304700159..4700368-210WP_003486601.1CsbD family protein-
AMD10_RS206354700595..4700729-135WP_005914328.1entericidin A/B family lipoproteinToxin
AMD10_RS206404700804..4700956-153WP_003486606.1entericidin A/B family lipoproteinAntitoxin
AMD10_RS206454701063..4701986-924WP_005927745.1arginase-
AMD10_RS206504702307..4702759+453WP_003486611.1roadblock/LC7 domain-containing protein-
AMD10_RS206554702823..4703182+360WP_003486613.1hypothetical protein-
AMD10_RS206604703279..4704196+918WP_011052673.1hypothetical protein-
AMD10_RS206654704193..4704735+543WP_003486615.1GTPase-
AMD10_RS206704705173..4705856+684WP_011052674.1dTMP kinase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48059 WP_005914328.1 NZ_CP009007:c4700729-4700595 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48059 NZ_CP009007:c4700729-4700595 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48059 WP_003486606.1 NZ_CP009007:c4700956-4700804 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48059 NZ_CP009007:c4700956-4700804 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A3G2W7U6

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A828YLX6

References