48051

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4649889..4650250 Replicon chromosome
Accession NZ_CP009004
Organism Xanthomonas citri pv. citri strain MN10

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD16_RS20495 Protein ID WP_005914328.1
Coordinates 4649889..4650023 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD16_RS20500 Protein ID WP_003486606.1
Coordinates 4650098..4650250 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD16_RS20475 4645027..4646718 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
AMD16_RS20480 4646910..4647944 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD16_RS20485 4647983..4649272 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD16_RS20490 4649453..4649662 - 210 WP_003486601.1 CsbD family protein -
AMD16_RS20495 4649889..4650023 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD16_RS20500 4650098..4650250 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD16_RS20505 4650357..4651280 - 924 WP_005927745.1 arginase -
AMD16_RS20510 4651601..4652053 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD16_RS20515 4652117..4652476 + 360 WP_003486613.1 hypothetical protein -
AMD16_RS20520 4652573..4653490 + 918 WP_011052673.1 hypothetical protein -
AMD16_RS20525 4653487..4654029 + 543 WP_003486615.1 GTPase -
AMD16_RS20530 4654467..4655150 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48051 WP_005914328.1 NZ_CP009004:c4650023-4649889 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48051 NZ_CP009004:c4650023-4649889 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48051 WP_003486606.1 NZ_CP009004:c4650250-4650098 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48051 NZ_CP009004:c4650250-4650098 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References