48043

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4648558..4648919 Replicon chromosome
Accession NZ_CP009001
Organism Xanthomonas citri pv. citri strain MN11

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD15_RS20465 Protein ID WP_005914328.1
Coordinates 4648558..4648692 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD15_RS20470 Protein ID WP_003486606.1
Coordinates 4648767..4648919 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD15_RS20445 4643696..4645387 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
AMD15_RS20450 4645579..4646613 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD15_RS20455 4646652..4647941 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD15_RS20460 4648122..4648331 - 210 WP_003486601.1 CsbD family protein -
AMD15_RS20465 4648558..4648692 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD15_RS20470 4648767..4648919 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD15_RS20475 4649026..4649949 - 924 WP_005927745.1 arginase -
AMD15_RS20480 4650270..4650722 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD15_RS20485 4650786..4651145 + 360 WP_003486613.1 hypothetical protein -
AMD15_RS20490 4651242..4652159 + 918 WP_011052673.1 hypothetical protein -
AMD15_RS20495 4652156..4652698 + 543 WP_003486615.1 GTPase -
AMD15_RS20500 4653136..4653819 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48043 WP_005914328.1 NZ_CP009001:c4648692-4648558 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48043 NZ_CP009001:c4648692-4648558 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48043 WP_003486606.1 NZ_CP009001:c4648919-4648767 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48043 NZ_CP009001:c4648919-4648767 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References