Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 50428..51086 Replicon plasmid pXAC64
Accession NZ_CP008997
Organism Xanthomonas citri pv. citri strain MN12

Toxin (Protein)


Gene name vapC Uniprot ID Q8PRH3
Locus tag AMD14_RS00435 Protein ID WP_011053002.1
Coordinates 50428..50829 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4U2L0
Locus tag AMD14_RS00440 Protein ID WP_011053003.1
Coordinates 50826..51086 (-) Length 87 a.a.

Genomic Context

AMD14_RS00445AMD14_RS00415AMD14_RS00420AMD14_RS00425AMD14_RS00430AMD14_RS00435AMD14_RS00440AMD14_RS00450
Location: 51277..51849 (573 bp)
Type: Others
Protein ID: WP_011053004.1
Location: 45868..46635 (768 bp)
Type: Others
Protein ID: WP_011052998.1
Location: 47440..48666 (1227 bp)
Type: Others
Protein ID: WP_015472949.1
Location: 48946..50133 (1188 bp)
Type: Others
Protein ID: WP_011053001.1
Location: 50140..50403 (264 bp)
Type: Others
Protein ID: WP_005917846.1
Location: 50428..50829 (402 bp)
Type: Toxin
Protein ID: WP_011053002.1
Location: 50826..51086 (261 bp)
Type: Antitoxin
Protein ID: WP_011053003.1
Location: 51880..52468 (589 bp)
Type: Others
Protein ID: Protein_59
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AMD14_RS0041545868..46635-768WP_011052998.1ParA family protein-
AMD14_RS0042047440..48666-1227WP_015472949.1plasmid replication initiator protein-
AMD14_RS0042548946..50133-1188WP_011053001.1zeta toxin family protein-
AMD14_RS0043050140..50403-264WP_005917846.1hypothetical protein-
AMD14_RS0043550428..50829-402WP_011053002.1type II toxin-antitoxin system VapC family toxinToxin
AMD14_RS0044050826..51086-261WP_011053003.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
AMD14_RS0044551277..51849+573WP_011053004.1recombinase family protein-
AMD14_RS0045051880..52468-589Protein_59IS3 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..6372163721


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

SpoVT-AbrB domain

(8-46)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14627.05 Da        Isoelectric Point: 7.2785

>T48031 WP_011053002.1 NZ_CP008997:c50829-50428 [Xanthomonas citri pv. citri]
MKRYMLDTNTVSHLVKSHPAVSRRVIEVPMTALCMSAITGGELMFGLAKVPDAKRLQQAVMELLRRVDVLPWDGAVMERY
GSVRADLEKQGKALGSLDMLIAAHALETDSVLVTNDAAFSRVVGLTVEDWTRS

Download         Length: 402 bp

>T48031 NZ_CP008997:c50829-50428 [Xanthomonas citri pv. citri]
ATGAAGCGGTACATGCTTGATACCAACACCGTGAGCCATCTCGTCAAGAGCCATCCGGCTGTCTCTCGACGGGTCATTGA
AGTGCCTATGACTGCGCTATGTATGTCCGCAATTACCGGTGGGGAGCTGATGTTCGGCTTGGCTAAGGTGCCAGACGCCA
AACGCCTTCAGCAAGCCGTCATGGAACTCCTGCGGCGCGTGGATGTGCTGCCTTGGGATGGCGCGGTAATGGAGCGTTAC
GGAAGCGTAAGAGCGGACCTAGAAAAGCAAGGTAAAGCGCTTGGGTCGCTCGACATGCTTATCGCAGCACATGCACTGGA
AACGGATTCTGTCCTCGTTACCAATGACGCCGCATTTAGTCGTGTTGTTGGTTTGACCGTGGAAGATTGGACACGCAGCT
AA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9799.00 Da        Isoelectric Point: 5.0941

>AT48031 WP_011053003.1 NZ_CP008997:c51086-50826 [Xanthomonas citri pv. citri]
VSQVAKLFINGRSQAVRLPAAYRFTEKEVFIRQDPETGDVILSRKPATWEDFFIVLKSADVPANFLDAAERNQGTQDRDP
FAGWRE

Download         Length: 261 bp

>AT48031 NZ_CP008997:c51086-50826 [Xanthomonas citri pv. citri]
GTGAGCCAAGTTGCCAAGCTGTTCATCAATGGCCGCAGCCAGGCAGTCCGCTTGCCTGCCGCCTATCGCTTTACCGAGAA
AGAGGTTTTCATTCGCCAAGACCCGGAGACCGGTGACGTCATCCTGTCTCGGAAGCCTGCAACGTGGGAGGACTTCTTTA
TCGTACTCAAGAGCGCAGATGTGCCTGCTAATTTTCTAGATGCCGCCGAGCGCAATCAGGGCACGCAGGACCGTGATCCT
TTTGCGGGATGGCGCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBQ8PRH3

Antitoxin

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Source
ID
Structure
AlphaFold DBM4U2L0

References