Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5099885..5100552 Replicon chromosome
Accession NZ_CP008995
Organism Xanthomonas citri pv. citri strain NT17

Toxin (Protein)


Gene name vapC Uniprot ID M4U0C6
Locus tag AMD13_RS22210 Protein ID WP_005916679.1
Coordinates 5100136..5100552 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4U000
Locus tag AMD13_RS22205 Protein ID WP_005916676.1
Coordinates 5099885..5100139 (+) Length 85 a.a.

Genomic Context

AMD13_RS22180AMD13_RS22185AMD13_RS22195AMD13_RS22200AMD13_RS22205AMD13_RS22210AMD13_RS22215AMD13_RS22225AMD13_RS22190AMD13_RS25085AMD13_RS25090AMD13_RS22220AMD13_RS24575
Location: 5096007..5096226 (220 bp)
Type: Others
Protein ID: Protein_4256
Location: 5096383..5097648 (1266 bp)
Type: Others
Protein ID: WP_015463799.1
Location: 5098440..5098646 (207 bp)
Type: Others
Protein ID: WP_003489327.1
Location: 5098633..5099739 (1107 bp)
Type: Others
Protein ID: WP_005916674.1
Location: 5099885..5100139 (255 bp)
Type: Antitoxin
Protein ID: WP_005916676.1
Location: 5100136..5100552 (417 bp)
Type: Toxin
Protein ID: WP_005916679.1
Location: 5101474..5103093 (1620 bp)
Type: Others
Protein ID: WP_015463800.1
Location: 5103911..5104342 (432 bp)
Type: Others
Protein ID: WP_005922907.1
Location: 5097674..5098201 (528 bp)
Type: Others
Protein ID: WP_005916668.1
Location: 5100674..5100877 (204 bp)
Type: Others
Protein ID: WP_125460668.1
Location: 5101005..5101217 (213 bp)
Type: Others
Protein ID: WP_015472901.1
Location: 5103197..5103595 (399 bp)
Type: Others
Protein ID: WP_004429277.1
Location: 5104371..5104697 (327 bp)
Type: Others
Protein ID: Protein_4268
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AMD13_RS221805096007..5096226+220Protein_4256RNA 2'-phosphotransferase-
AMD13_RS221855096383..5097648+1266WP_015463799.1cardiolipin synthase B-
AMD13_RS221905097674..5098201-528WP_005916668.1hypothetical protein-
AMD13_RS221955098440..5098646+207WP_003489327.1hypothetical protein-
AMD13_RS222005098633..5099739+1107WP_005916674.1type II toxin-antitoxin system RelE/ParE family toxin-
AMD13_RS222055099885..5100139+255WP_005916676.1Arc family DNA-binding proteinAntitoxin
AMD13_RS222105100136..5100552+417WP_005916679.1type II toxin-antitoxin system VapC family toxinToxin
AMD13_RS250855100674..5100877-204WP_125460668.1hypothetical protein-
AMD13_RS250905101005..5101217-213WP_015472901.1hypothetical protein-
AMD13_RS222155101474..5103093+1620WP_015463800.1hypothetical protein-
AMD13_RS222205103197..5103595-399WP_004429277.1DUF2384 domain-containing protein-
AMD13_RS222255103911..5104342+432WP_005922907.1hypothetical protein-
AMD13_RS245755104371..5104697-327Protein_4268hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14795.09 Da        Isoelectric Point: 5.6920

>T48028 WP_005916679.1 NZ_CP008995:5100136-5100552 [Xanthomonas citri pv. citri]
VILLDTNVISELWRPQPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPKGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFAALASKARTAGLTLGRADAYIAATAAAQGLTVATRDTAPFEAMALDVINPWS

Download         Length: 417 bp

>T48028 NZ_CP008995:5100136-5100552 [Xanthomonas citri pv. citri]
GTGATCCTGCTCGATACCAATGTCATCTCCGAACTTTGGCGGCCTCAGCCTAATCCGCAGGTCGTCGCCTGGATCGATGC
ACAAGCTGTCGAGACACTGTTCCTGTCGGTCGTGACGGTGGCTGAACTCCGTTTCGGTATTGCCGTGATGCCCAAGGGCC
GAAAGCGATCCACCTTGCATGCTCGGTTGGAGGGCGAGGTATTGCCACTGTTCGACGGGCGCCTGCTCGCATTCGATCTG
GATGCATCACACGCATTTGCGGCGCTTGCATCGAAAGCCAGAACCGCAGGACTCACACTCGGGCGCGCCGATGCCTACAT
CGCTGCAACAGCAGCCGCGCAAGGATTGACCGTTGCCACTCGCGACACGGCACCATTCGAGGCGATGGCGTTAGACGTCA
TTAACCCTTGGAGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8996.53 Da        Isoelectric Point: 11.3362

>AT48028 WP_005916676.1 NZ_CP008995:5099885-5100139 [Xanthomonas citri pv. citri]
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILELAAKPADRVKLGSLLVSIGRDAGLTAKEANAFDKLRGKAAIKP
IGLK

Download         Length: 255 bp

>AT48028 NZ_CP008995:5099885-5100139 [Xanthomonas citri pv. citri]
ATGCCTTCTTTCACCGTCCGCAATATCCCAGACGACGTGCATCGCGCGATCCGCGCGCGGGCTGCACTTCATGGCCGCAG
CACCGAAGCGGAGATCCGCGCAATCCTTGAATTGGCGGCCAAACCCGCAGACCGGGTCAAACTCGGCTCACTGCTGGTGA
GCATCGGCCGCGACGCCGGCCTGACCGCAAAAGAGGCCAATGCCTTCGACAAGCTGCGCGGCAAGGCGGCGATCAAGCCG
ATCGGTCTGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBM4U0C6

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A828YKJ0

References