Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4648948..4649309 Replicon chromosome
Accession NZ_CP008992
Organism Xanthomonas citri subsp. citri UI6

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD19_RS20505 Protein ID WP_005914328.1
Coordinates 4648948..4649082 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD19_RS20510 Protein ID WP_003486606.1
Coordinates 4649157..4649309 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD19_RS20485 4644086..4645777 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
AMD19_RS20490 4645969..4647003 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD19_RS20495 4647042..4648331 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD19_RS20500 4648512..4648721 - 210 WP_003486601.1 CsbD family protein -
AMD19_RS20505 4648948..4649082 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD19_RS20510 4649157..4649309 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD19_RS20515 4649416..4650339 - 924 WP_005927745.1 arginase -
AMD19_RS20520 4650660..4651112 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD19_RS20525 4651176..4651535 + 360 WP_003486613.1 hypothetical protein -
AMD19_RS20530 4651632..4652549 + 918 WP_011052673.1 hypothetical protein -
AMD19_RS20535 4652546..4653088 + 543 WP_003486615.1 GTPase -
AMD19_RS20540 4653526..4654209 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48019 WP_005914328.1 NZ_CP008992:c4649082-4648948 [Xanthomonas citri subsp. citri UI6]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48019 NZ_CP008992:c4649082-4648948 [Xanthomonas citri subsp. citri UI6]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48019 WP_003486606.1 NZ_CP008992:c4649309-4649157 [Xanthomonas citri subsp. citri UI6]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48019 NZ_CP008992:c4649309-4649157 [Xanthomonas citri subsp. citri UI6]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References