Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4648948..4649309 Replicon chromosome
Accession NZ_CP008992
Organism Xanthomonas citri subsp. citri UI6

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD19_RS20505 Protein ID WP_005914328.1
Coordinates 4648948..4649082 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD19_RS20510 Protein ID WP_003486606.1
Coordinates 4649157..4649309 (-) Length 51 a.a.

Genomic Context

AMD19_RS20520AMD19_RS20525AMD19_RS20530AMD19_RS20535AMD19_RS20540AMD19_RS20485AMD19_RS20490AMD19_RS20495AMD19_RS20500AMD19_RS20505AMD19_RS20510AMD19_RS20515
Location: 4650660..4651112 (453 bp)
Type: Others
Protein ID: WP_003486611.1
Location: 4651176..4651535 (360 bp)
Type: Others
Protein ID: WP_003486613.1
Location: 4651632..4652549 (918 bp)
Type: Others
Protein ID: WP_011052673.1
Location: 4652546..4653088 (543 bp)
Type: Others
Protein ID: WP_003486615.1
Location: 4653526..4654209 (684 bp)
Type: Others
Protein ID: WP_011052674.1
Location: 4644086..4645777 (1692 bp)
Type: Others
Protein ID: WP_015471463.1
Location: 4645969..4647003 (1035 bp)
Type: Others
Protein ID: WP_011052671.1
Location: 4647042..4648331 (1290 bp)
Type: Others
Protein ID: WP_015463705.1
Location: 4648512..4648721 (210 bp)
Type: Others
Protein ID: WP_003486601.1
Location: 4648948..4649082 (135 bp)
Type: Toxin
Protein ID: WP_005914328.1
Location: 4649157..4649309 (153 bp)
Type: Antitoxin
Protein ID: WP_003486606.1
Location: 4649416..4650339 (924 bp)
Type: Others
Protein ID: WP_005927745.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AMD19_RS204854644086..4645777-1692WP_015471463.1M20/M25/M40 family metallo-hydrolase-
AMD19_RS204904645969..4647003-1035WP_011052671.1MBL fold metallo-hydrolase-
AMD19_RS204954647042..4648331-1290WP_015463705.1tryptophan--tRNA ligase-
AMD19_RS205004648512..4648721-210WP_003486601.1CsbD family protein-
AMD19_RS205054648948..4649082-135WP_005914328.1entericidin A/B family lipoproteinToxin
AMD19_RS205104649157..4649309-153WP_003486606.1entericidin A/B family lipoproteinAntitoxin
AMD19_RS205154649416..4650339-924WP_005927745.1arginase-
AMD19_RS205204650660..4651112+453WP_003486611.1roadblock/LC7 domain-containing protein-
AMD19_RS205254651176..4651535+360WP_003486613.1hypothetical protein-
AMD19_RS205304651632..4652549+918WP_011052673.1hypothetical protein-
AMD19_RS205354652546..4653088+543WP_003486615.1GTPase-
AMD19_RS205404653526..4654209+684WP_011052674.1dTMP kinase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48019 WP_005914328.1 NZ_CP008992:c4649082-4648948 [Xanthomonas citri subsp. citri UI6]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48019 NZ_CP008992:c4649082-4648948 [Xanthomonas citri subsp. citri UI6]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48019 WP_003486606.1 NZ_CP008992:c4649309-4649157 [Xanthomonas citri subsp. citri UI6]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48019 NZ_CP008992:c4649309-4649157 [Xanthomonas citri subsp. citri UI6]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A3G2W7U6

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A828YLX6

References