48011

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4648805..4649166 Replicon chromosome
Accession NZ_CP008989
Organism Xanthomonas citri pv. citri strain UI7

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AMD18_RS20485 Protein ID WP_005914328.1
Coordinates 4648805..4648939 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AMD18_RS20490 Protein ID WP_003486606.1
Coordinates 4649014..4649166 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD18_RS20465 4643943..4645634 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
AMD18_RS20470 4645826..4646860 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
AMD18_RS20475 4646899..4648188 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
AMD18_RS20480 4648369..4648578 - 210 WP_003486601.1 CsbD family protein -
AMD18_RS20485 4648805..4648939 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AMD18_RS20490 4649014..4649166 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AMD18_RS20495 4649273..4650196 - 924 WP_005927745.1 arginase -
AMD18_RS20500 4650517..4650969 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
AMD18_RS20505 4651033..4651392 + 360 WP_003486613.1 hypothetical protein -
AMD18_RS20510 4651489..4652406 + 918 WP_011052673.1 hypothetical protein -
AMD18_RS20515 4652403..4652945 + 543 WP_003486615.1 GTPase -
AMD18_RS20520 4653383..4654066 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T48011 WP_005914328.1 NZ_CP008989:c4648939-4648805 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T48011 NZ_CP008989:c4648939-4648805 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT48011 WP_003486606.1 NZ_CP008989:c4649166-4649014 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT48011 NZ_CP008989:c4649166-4649014 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References