Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2619359..2619630 Replicon chromosome
Accession NZ_CP008957
Organism Escherichia coli O157:H7 str. EDL933

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2619397..2619500 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2619359..2619630 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EDL933_RS13725 2616516..2617955 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EDL933_RS13730 2618073..2618309 + 237 WP_001295499.1 DUF1480 family protein -
EDL933_RS13735 2618414..2618605 + 192 WP_001296140.1 YebW family protein -
EDL933_RS13740 2618606..2619262 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2619359..2619630 + 272 - - Antitoxin
- 2619397..2619500 - 104 - - Toxin
EDL933_RS13750 2619658..2619999 - 342 WP_000976483.1 YebY family protein -
EDL933_RS13755 2620012..2620884 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
EDL933_RS13760 2620888..2621262 - 375 WP_000168751.1 CopC domain-containing protein YobA -
EDL933_RS13765 2621401..2621631 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EDL933_RS13770 2621733..2622389 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
EDL933_RS13775 2622413..2623075 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T47983 NZ_CP008957:c2619500-2619397 [Escherichia coli O157:H7 str. EDL933]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT47983 NZ_CP008957:2619359-2619630 [Escherichia coli O157:H7 str. EDL933]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References