Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1355624..1356392 Replicon chromosome
Accession NZ_CP008943
Organism Yersinia pseudotuberculosis strain ATCC 6904

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag DJ40_RS06165 Protein ID WP_038400133.1
Coordinates 1355624..1355992 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag DJ40_RS06170 Protein ID WP_038400135.1
Coordinates 1356018..1356392 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DJ40_RS06125 1350938..1351540 - 603 WP_002209770.1 CDP-alcohol phosphatidyltransferase family protein -
DJ40_RS06135 1351940..1352146 - 207 WP_002354559.1 hypothetical protein -
DJ40_RS22255 1352358..1352636 + 279 WP_080619191.1 tyrosine-type recombinase/integrase -
DJ40_RS06140 1352719..1353057 + 339 WP_002215266.1 hypothetical protein -
DJ40_RS06145 1353042..1353689 + 648 WP_012105552.1 hypothetical protein -
DJ40_RS06150 1353803..1354003 + 201 WP_002215268.1 hypothetical protein -
DJ40_RS06155 1354262..1354444 + 183 WP_038400129.1 AlpA family phage regulatory protein -
DJ40_RS06160 1354658..1355491 - 834 WP_038400131.1 DUF4942 domain-containing protein -
DJ40_RS06165 1355624..1355992 - 369 WP_038400133.1 TA system toxin CbtA family protein Toxin
DJ40_RS06170 1356018..1356392 - 375 WP_038400135.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
DJ40_RS06175 1356413..1356634 - 222 WP_038400137.1 DUF987 domain-containing protein -
DJ40_RS06180 1356645..1357172 - 528 WP_080725838.1 DNA repair protein RadC -
DJ40_RS06185 1357185..1357649 - 465 WP_038400140.1 antirestriction protein -
DJ40_RS22265 1357790..1357954 - 165 WP_162472803.1 DUF905 family protein -
DJ40_RS06195 1357980..1358813 - 834 WP_038400142.1 DUF945 domain-containing protein -
DJ40_RS06200 1358957..1359313 - 357 WP_038400144.1 hypothetical protein -
DJ40_RS06205 1359368..1359859 - 492 WP_200876960.1 hypothetical protein -
DJ40_RS06210 1359862..1360416 - 555 WP_038400146.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(15-114)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13576.31 Da        Isoelectric Point: 5.6907

>T47961 WP_038400133.1 NZ_CP008943:c1355992-1355624 [Yersinia pseudotuberculosis]
MKTQSASQALAASSRPSPVEIWQTLLTYLLDQHYGMTQNDTPFGNDGVIQEHIDAGISLCDAVNFIVEKYDLVRTDRRGF
SAEEQSPLISSIDILRARRATGLMTRLGYQTITSVIRGEKQT

Download         Length: 369 bp

>T47961 NZ_CP008943:c1355992-1355624 [Yersinia pseudotuberculosis]
ATGAAAACACAATCAGCTTCCCAGGCGCTGGCGGCTTCGTCACGCCCGTCCCCTGTTGAAATCTGGCAGACGCTACTGAC
GTACCTGCTGGACCAGCACTATGGCATGACGCAGAACGACACGCCGTTTGGCAATGACGGTGTGATCCAGGAACACATTG
ACGCCGGTATTTCACTGTGTGACGCGGTGAATTTTATCGTGGAGAAATATGACCTGGTGCGTACTGACCGTCGCGGCTTC
AGCGCAGAAGAACAATCGCCACTTATCAGCAGTATCGATATTCTCCGTGCCCGTCGAGCCACTGGCCTGATGACCCGTCT
GGGTTACCAGACCATCACCTCAGTTATCCGGGGCGAAAAGCAGACATGA

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14101.11 Da        Isoelectric Point: 7.0271

>AT47961 WP_038400135.1 NZ_CP008943:c1356392-1356018 [Yersinia pseudotuberculosis]
MQKETHTTHHALSEPWWGLRRDVTPCFGARLVQEGNRLHYLADRASITGTFSDAERLHIDQAFPVLLKQLELMLLSGELN
PQRQHSIILYAKGLTCEADCLASCGYLYLAIYPTTATAEYPQRR

Download         Length: 375 bp

>AT47961 NZ_CP008943:c1356392-1356018 [Yersinia pseudotuberculosis]
ATGCAGAAAGAAACCCACACTACACACCACGCTCTCTCTGAGCCATGGTGGGGCCTGCGACGCGATGTCACCCCGTGTTT
TGGCGCTCGCCTGGTGCAGGAAGGCAACCGGCTGCATTACCTGGCCGATCGCGCCAGTATCACCGGCACCTTCAGCGACG
CAGAACGGCTTCATATTGACCAGGCCTTTCCGGTACTGCTGAAGCAACTGGAGCTCATGTTGCTTTCCGGTGAACTCAAT
CCCCAGCGTCAGCACTCAATCATCCTGTATGCGAAAGGGTTGACCTGCGAAGCGGACTGCCTGGCAAGCTGCGGTTACCT
CTACCTCGCGATTTACCCAACGACTGCAACAGCCGAATACCCCCAACGTCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References