47936

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5068495..5068640 Replicon chromosome
Accession NZ_CP008929
Organism Klebsiella pneumoniae strain PMK1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5068502..5068604 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5068495..5068640 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PMK1_RS24780 5064026..5065459 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PMK1_RS24785 5065575..5065814 + 240 WP_002911393.1 YebV family protein -
PMK1_RS24790 5065912..5066103 + 192 WP_002911395.1 YebW family protein -
PMK1_RS24795 5066100..5066753 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
PMK1_RS24800 5066910..5067878 + 969 WP_004151446.1 VirK/YbjX family protein -
PMK1_RS32230 5067983..5068126 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5068495..5068640 + 146 - - Antitoxin
- 5068502..5068604 - 103 - - Toxin
PMK1_RS24810 5068763..5069101 - 339 WP_002911404.1 YebY family protein -
PMK1_RS24815 5069118..5069987 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
PMK1_RS24820 5069991..5070365 - 375 WP_004151448.1 CopC domain-containing protein YobA -
PMK1_RS24825 5070478..5070708 + 231 WP_002911406.1 DNA polymerase III subunit theta -
PMK1_RS24830 5070787..5071446 + 660 WP_020324964.1 exodeoxyribonuclease X -
PMK1_RS24835 5071450..5073510 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T47936 NZ_CP008929:c5068604-5068502 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT47936 NZ_CP008929:5068495-5068640 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References