Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 3510953..3511686 Replicon chromosome
Accession NZ_CP008897
Organism Enterobacter hormaechei subsp. hoffmannii ECNIH3

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag ECNIH3_RS24960 Protein ID WP_043491403.1
Coordinates 3511357..3511686 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag ECNIH3_RS16485 Protein ID WP_038416562.1
Coordinates 3510953..3511318 (+) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECNIH3_RS26265 3506212..3506361 + 150 WP_001458941.1 hypothetical protein -
ECNIH3_RS16445 3506373..3506588 + 216 WP_038416553.1 hypothetical protein -
ECNIH3_RS16450 3506733..3507143 + 411 WP_038416555.1 hypothetical protein -
ECNIH3_RS25730 3507209..3508147 + 939 WP_077887331.1 hypothetical protein -
ECNIH3_RS16460 3508221..3508454 + 234 WP_038416556.1 DUF905 domain-containing protein -
ECNIH3_RS16465 3508568..3509386 + 819 WP_038416557.1 DUF945 domain-containing protein -
ECNIH3_RS24955 3509386..3509640 + 255 WP_071881512.1 hypothetical protein -
ECNIH3_RS16470 3509737..3510204 + 468 WP_038416558.1 antirestriction protein -
ECNIH3_RS16475 3510215..3510694 + 480 WP_043491407.1 DNA repair protein RadC -
ECNIH3_RS16480 3510706..3510927 + 222 WP_038416561.1 DUF987 family protein -
ECNIH3_RS16485 3510953..3511318 + 366 WP_038416562.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
ECNIH3_RS24960 3511357..3511686 + 330 WP_043491403.1 TA system toxin CbtA family protein Toxin
ECNIH3_RS16490 3512056..3513054 + 999 Protein_3240 integrase arm-type DNA-binding domain-containing protein -
ECNIH3_RS26085 3513063..3513371 - 309 Protein_3241 DDE-type integrase/transposase/recombinase -
ECNIH3_RS16495 3513388..3514464 - 1077 WP_000227970.1 IS110 family transposase -
ECNIH3_RS25740 3514746..3515605 - 860 Protein_3243 IS3 family transposase -
ECNIH3_RS25745 3515574..3515747 - 174 WP_080298784.1 chromosome partitioning protein ParA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3505503..3533196 27693


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(17-117)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12384.08 Da        Isoelectric Point: 6.8692

>T47882 WP_043491403.1 NZ_CP008897:3511357-3511686 [Enterobacter hormaechei subsp. hoffmannii ECNIH3]
MQTLSLHPTRATPLCLSPVETWQRLLAHLFSQHYGLTLNDTPFSNETTIREHIDAGVSLSDAVNFLVEKYGLVRIDREGF
SWQEQTPYISAVDILRARRSTGLLKTDVK

Download         Length: 330 bp

>T47882 NZ_CP008897:3511357-3511686 [Enterobacter hormaechei subsp. hoffmannii ECNIH3]
ATGCAAACTTTATCATTACACCCGACTCGGGCGACTCCGCTCTGTTTGTCACCCGTTGAAACCTGGCAACGGCTACTGGC
TCATCTGTTCTCGCAGCACTATGGCCTGACGCTGAATGACACACCATTCAGTAATGAAACCACCATCCGGGAACATATTG
ATGCCGGAGTATCGCTCAGCGATGCGGTGAACTTTCTGGTAGAAAAATACGGACTTGTTCGTATCGACCGGGAGGGATTT
TCATGGCAAGAGCAAACTCCGTATATTTCCGCAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTGA
CGTGAAATAA

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13509.23 Da        Isoelectric Point: 4.7952

>AT47882 WP_038416562.1 NZ_CP008897:3510953-3511318 [Enterobacter hormaechei subsp. hoffmannii ECNIH3]
MNNHSESGTKPENPACKQWGLRCTITPCFGARLVQEGNRVHFLADRAGFNGAFSDEDVLRLDQAFSLILKQLELMLTSGE
LNPLYQHCVTLYHNGLTCEADTLGSFGYVYIAIYPDQPEPQ

Download         Length: 366 bp

>AT47882 NZ_CP008897:3510953-3511318 [Enterobacter hormaechei subsp. hoffmannii ECNIH3]
ATGAACAATCACTCCGAATCCGGAACTAAGCCGGAGAATCCCGCCTGCAAGCAGTGGGGACTAAGGTGCACGATCACACC
CTGTTTTGGCGCTCGCCTAGTGCAGGAGGGCAACCGGGTGCATTTTCTCGCTGATCGGGCCGGATTCAACGGTGCTTTCA
GTGACGAGGATGTGTTACGCCTAGACCAAGCTTTTTCACTGATACTCAAGCAACTGGAGCTAATGCTCACCAGCGGCGAG
CTAAATCCCCTCTATCAGCACTGCGTCACGCTTTACCACAACGGGCTCACCTGCGAAGCCGATACACTGGGCTCCTTTGG
TTATGTCTACATTGCTATTTATCCTGACCAGCCTGAACCGCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References