Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 3868669..3869594 Replicon chromosome
Accession NZ_CP008863
Organism Pseudomonas aeruginosa strain M37351

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag HW03_RS17825 Protein ID WP_170868735.1
Coordinates 3869268..3869594 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag HW03_RS17820 Protein ID WP_003111464.1
Coordinates 3868669..3869196 (+) Length 176 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HW03_RS17795 3863696..3863983 - 288 WP_003137130.1 hypothetical protein -
HW03_RS17800 3864075..3864551 - 477 WP_003118626.1 MarR family transcriptional regulator -
HW03_RS17805 3864592..3866082 - 1491 WP_003137133.1 UbiD family decarboxylase -
HW03_RS17810 3866216..3866902 - 687 WP_003106170.1 DUF1275 domain-containing protein -
HW03_RS17815 3867066..3867998 - 933 WP_003084116.1 hypothetical protein -
HW03_RS17820 3868669..3869196 + 528 WP_003111464.1 SocA family protein Antitoxin
HW03_RS17825 3869268..3869594 + 327 WP_170868735.1 hypothetical protein Toxin
HW03_RS32685 3871036..3872478 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(18-128)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12385.38 Da        Isoelectric Point: 9.1081

>T47766 WP_170868735.1 NZ_CP008863:3869268-3869594 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLRDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

>T47766 NZ_CP008863:3869268-3869594 [Pseudomonas aeruginosa]
ATGAATGACCCCGTGTACTGCCCGGTTCTTGGGTATGACGCGGTGTTGCTTGTCAACATCTCGACTGTCTATCCAGATAA
GTATTTCGATCAGTCATGCATTCTAAAGAAGGGTTGTCATCCCTTTGTTCTGCGCGACAGCTGGGTCGTATACCGCGAGG
CAGGCCCTTTCAACCTTGCACGGCTTGAGCAAGGGGTAGCGCAGAAGTCCATCAAGACGCATCAGCCCATCAACGCAGGC
GATTTCACTCGGATTCGGGCAGGCTTCGACATCTCGCCCGACGTCAAAATCAAAGTTGAGCGGTTCATGAGGCAGCACAA
GATTTAG

Antitoxin


Download         Length: 176 a.a.        Molecular weight: 20237.82 Da        Isoelectric Point: 5.7215

>AT47766 WP_003111464.1 NZ_CP008863:3868669-3869196 [Pseudomonas aeruginosa]
MAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAWISPLVDHEVR
LVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQSEELAEIKARD
LAERRRHGRKLSEFI

Download         Length: 528 bp

>AT47766 NZ_CP008863:3868669-3869196 [Pseudomonas aeruginosa]
ATGGCAGCTTTCTTTTTGGCGAGTGCCGAAGGGCCGCTGCCTCATCTCACGCTGATCAAACTGCTGTACCTGGCAGACCG
AGAGTCGATGGCTCGTTTCGACGTTCCCATGTCGGACGATCGAGCTGTTTCCATGCCCCATGGGCCTGTCCTTTCCTCGA
CGCTAGACCTCATCAAGGGGCGTTTGCGCTCTGAGGTTTGGAGCGCTTGGATTTCTCCGTTGGTGGATCACGAGGTCCGT
CTGGTCCATGACGTGGAGAATTGGGACGATCTGGATGAGTTGAGCCGATCGGATCGCAGCATTTTGGAATCGGTCTGGCA
AGAGTTTGGCCACATGACCAAGTACCAATTGCGGGACTACACCCACCATCACATTGGTGAGTGGCACGACCCCCACGGCT
CTTCCAGGGACATTGATCCAAAGGATACTTTCATGGCGCTTGGTCAAAGCGAGGAGCTGGCGGAGATCAAGGCGCGCGAT
CTTGCTGAGCGCCGTCGGCACGGTAGGAAGCTGTCTGAGTTCATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References