Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 316733..317658 Replicon chromosome
Accession NZ_CP008862
Organism Pseudomonas aeruginosa strain M1608

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag HW04_RS01570 Protein ID WP_170868735.1
Coordinates 317332..317658 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag HW04_RS01565 Protein ID WP_003111464.1
Coordinates 316733..317260 (+) Length 176 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HW04_RS01540 311760..312047 - 288 WP_003137130.1 hypothetical protein -
HW04_RS01545 312139..312615 - 477 WP_003118626.1 MarR family transcriptional regulator -
HW04_RS01550 312656..314146 - 1491 WP_003137133.1 UbiD family decarboxylase -
HW04_RS01555 314280..314966 - 687 WP_003106170.1 DUF1275 domain-containing protein -
HW04_RS01560 315130..316062 - 933 WP_003084116.1 hypothetical protein -
HW04_RS01565 316733..317260 + 528 WP_003111464.1 SocA family protein Antitoxin
HW04_RS01570 317332..317658 + 327 WP_170868735.1 hypothetical protein Toxin
HW04_RS01580 319100..320542 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(18-128)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12385.38 Da        Isoelectric Point: 9.1081

>T47758 WP_170868735.1 NZ_CP008862:317332-317658 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLRDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

>T47758 NZ_CP008862:317332-317658 [Pseudomonas aeruginosa]
ATGAATGACCCCGTGTACTGCCCGGTTCTTGGGTATGACGCGGTGTTGCTTGTCAACATCTCGACTGTCTATCCAGATAA
GTATTTCGATCAGTCATGCATTCTAAAGAAGGGTTGTCATCCCTTTGTTCTGCGCGACAGCTGGGTCGTATACCGCGAGG
CAGGCCCTTTCAACCTTGCACGGCTTGAGCAAGGGGTAGCGCAGAAGTCCATCAAGACGCATCAGCCCATCAACGCAGGC
GATTTCACTCGGATTCGGGCAGGCTTCGACATCTCGCCCGACGTCAAAATCAAAGTTGAGCGGTTCATGAGGCAGCACAA
GATTTAG

Antitoxin


Download         Length: 176 a.a.        Molecular weight: 20237.82 Da        Isoelectric Point: 5.7215

>AT47758 WP_003111464.1 NZ_CP008862:316733-317260 [Pseudomonas aeruginosa]
MAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAWISPLVDHEVR
LVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQSEELAEIKARD
LAERRRHGRKLSEFI

Download         Length: 528 bp

>AT47758 NZ_CP008862:316733-317260 [Pseudomonas aeruginosa]
ATGGCAGCTTTCTTTTTGGCGAGTGCCGAAGGGCCGCTGCCTCATCTCACGCTGATCAAACTGCTGTACCTGGCAGACCG
AGAGTCGATGGCTCGTTTCGACGTTCCCATGTCGGACGATCGAGCTGTTTCCATGCCCCATGGGCCTGTCCTTTCCTCGA
CGCTAGACCTCATCAAGGGGCGTTTGCGCTCTGAGGTTTGGAGCGCTTGGATTTCTCCGTTGGTGGATCACGAGGTCCGT
CTGGTCCATGACGTGGAGAATTGGGACGATCTGGATGAGTTGAGCCGATCGGATCGCAGCATTTTGGAATCGGTCTGGCA
AGAGTTTGGCCACATGACCAAGTACCAATTGCGGGACTACACCCACCATCACATTGGTGAGTGGCACGACCCCCACGGCT
CTTCCAGGGACATTGATCCAAAGGATACTTTCATGGCGCTTGGTCAAAGCGAGGAGCTGGCGGAGATCAAGGCGCGCGAT
CTTGCTGAGCGCCGTCGGCACGGTAGGAAGCTGTCTGAGTTCATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References