47712

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 2611496..2612873 Replicon chromosome
Accession NZ_CP008849
Organism Alteromonas australica strain H 17

Toxin (Protein)


Gene name sanaT Uniprot ID A0A075P0F2
Locus tag EP13_RS11540 Protein ID WP_044057417.1
Coordinates 2611496..2612488 (-) Length 331 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A0A075P7P9
Locus tag EP13_RS11545 Protein ID WP_044057418.1
Coordinates 2612469..2612873 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EP13_RS11520 2608129..2609325 - 1197 WP_044057413.1 HipA domain-containing protein -
EP13_RS11525 2609315..2609605 - 291 WP_044057414.1 helix-turn-helix domain-containing protein -
EP13_RS11530 2609822..2610274 - 453 WP_044057415.1 NfeD family protein -
EP13_RS11535 2610277..2611221 - 945 WP_044057416.1 paraslipin -
EP13_RS19260 2611240..2611461 - 222 WP_156026753.1 hypothetical protein -
EP13_RS11540 2611496..2612488 - 993 WP_044057417.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
EP13_RS11545 2612469..2612873 - 405 WP_044057418.1 hypothetical protein Antitoxin
EP13_RS19115 2613004..2613348 - 345 WP_081869498.1 tyrosine-type recombinase/integrase -
EP13_RS11555 2614015..2615427 - 1413 WP_044057419.1 SLC13 family permease -
EP13_RS11560 2615527..2616120 - 594 WP_044057420.1 dCTP deaminase -
EP13_RS11565 2616214..2617317 - 1104 WP_044057421.1 iron-sulfur cluster carrier protein ApbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-304)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 331 a.a.        Molecular weight: 37823.84 Da        Isoelectric Point: 4.8222

>T47712 WP_044057417.1 NZ_CP008849:c2612488-2611496 [Alteromonas australica]
VSTKLDSSLFVDVADAIGLGNPAIVEKDYYVVQLLKHLSIIEFEHHQLVFTGGTALAKSVIKTYRMSEDIDIKLVPNNVF
NNLTSRSARRKARKAVKQHIEFLISEGGTFSIEEQATVKDEYRYFSFDIRYPQAYQQAPCLRPFIKLEFIESDLLDEAES
KSIQSIYAEVLKSDIEVKNMECAAILETQAEKLLSMMRRTASVARNHERDDDETLIRHIYDTYHIQKAQPANIEALSNVV
TIAIELDVERFGNQHPQMVESPIDELCFGLQLLTDDPKFEERYNSYVSPMVYAESPVNWDNALAVFTKLANEVFQCIRED
SLNRPDFSRH

Download         Length: 993 bp

>T47712 NZ_CP008849:c2612488-2611496 [Alteromonas australica]
GTGTCAACGAAGCTCGATAGCTCGCTATTTGTCGATGTTGCCGACGCCATAGGGCTAGGCAACCCGGCAATTGTCGAAAA
GGACTACTATGTTGTCCAACTATTAAAGCACTTATCGATAATCGAATTCGAACACCACCAGTTGGTATTTACGGGCGGCA
CTGCACTTGCCAAGTCTGTTATAAAAACGTATCGCATGTCGGAAGATATCGATATTAAACTGGTTCCCAACAATGTATTT
AATAATCTAACATCACGAAGCGCTAGGCGAAAGGCTCGTAAAGCGGTTAAGCAGCATATTGAGTTTTTGATATCAGAGGG
CGGCACCTTTTCCATTGAAGAACAAGCTACTGTAAAGGATGAATATCGCTACTTCAGTTTTGATATCCGCTATCCTCAAG
CATACCAGCAAGCACCTTGCCTGCGACCTTTTATTAAATTGGAATTCATCGAATCAGATCTCCTAGATGAAGCTGAATCT
AAAAGCATTCAATCTATCTATGCCGAAGTCCTCAAATCTGATATTGAAGTAAAAAACATGGAATGCGCTGCAATCTTAGA
GACTCAAGCTGAAAAACTGTTATCAATGATGCGCAGAACGGCAAGCGTCGCCAGAAATCATGAACGTGATGACGACGAAA
CACTTATCAGGCATATCTACGACACGTACCATATCCAAAAGGCTCAGCCAGCAAATATAGAAGCGCTCAGCAACGTAGTG
ACAATCGCCATTGAATTAGATGTTGAACGTTTCGGTAATCAGCATCCACAAATGGTTGAATCTCCCATCGACGAGTTGTG
TTTCGGATTACAACTACTGACTGATGATCCCAAGTTTGAAGAAAGGTACAACAGCTATGTGAGCCCAATGGTTTATGCAG
AAAGCCCCGTGAATTGGGATAATGCGTTAGCGGTATTCACCAAATTGGCCAATGAAGTATTTCAATGTATTAGGGAAGAT
AGCTTGAATCGACCAGACTTCTCTAGACACTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15107.48 Da        Isoelectric Point: 10.9767

>AT47712 WP_044057418.1 NZ_CP008849:c2612873-2612469 [Alteromonas australica]
MTIQDRIKTRVKRSKRSVFLRSDFKDIADYDQVGRGLRSLAREGVLMKIGYGLYARARVNRITGKLMPDNAAGADGVLIE
AMERLDVGYKFDDLSNMNFLGQSTQIPASVKIVPTDPRFTRKISVGKQRVNEAR

Download         Length: 405 bp

>AT47712 NZ_CP008849:c2612873-2612469 [Alteromonas australica]
ATGACGATACAAGACAGGATAAAAACAAGAGTCAAGCGCTCTAAGCGTTCTGTTTTTTTGCGCTCCGATTTTAAAGATAT
AGCTGACTACGACCAAGTAGGTCGAGGCCTTAGAAGTCTTGCTCGTGAAGGCGTGTTGATGAAGATAGGTTACGGGCTTT
ATGCACGTGCCAGAGTCAATCGCATTACAGGTAAATTGATGCCTGACAATGCTGCGGGTGCTGATGGTGTATTAATAGAA
GCTATGGAAAGATTAGATGTAGGCTACAAGTTCGATGATTTGTCGAACATGAACTTTTTAGGCCAGAGTACGCAAATTCC
AGCCAGTGTTAAAATTGTTCCAACCGATCCACGCTTTACCCGTAAAATTTCCGTAGGTAAACAGCGTGTCAACGAAGCTC
GATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A075P0F2

Antitoxin

Source ID Structure
AlphaFold DB A0A075P7P9

References