47623

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT(toxin)
Location 2389248..2389810 Replicon chromosome
Accession NZ_CP008820
Organism Brucella anthropi strain OAB

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag DR92_RS24450 Protein ID WP_158304319.1
Coordinates 2389248..2389532 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag DR92_RS21565 Protein ID WP_144243804.1
Coordinates 2389529..2389810 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DR92_RS21520 2384436..2385329 - 894 WP_012090883.1 MurR/RpiR family transcriptional regulator -
DR92_RS21525 2385504..2385722 + 219 WP_040129737.1 hypothetical protein -
DR92_RS21530 2385736..2385990 + 255 WP_040129739.1 type II toxin-antitoxin system HicA family toxin -
DR92_RS24580 2386158..2386319 + 162 WP_140986072.1 toxin-antitoxin system HicB family antitoxin -
DR92_RS21540 2386474..2386900 - 427 Protein_2224 type IV secretory system conjugative DNA transfer family protein -
DR92_RS21545 2387202..2387456 - 255 WP_040129743.1 toxin-antitoxin system HicB family antitoxin -
DR92_RS21550 2387453..2387728 - 276 Protein_2226 PIN domain-containing protein -
DR92_RS21555 2387888..2389069 - 1182 WP_012090877.1 Fic family protein -
DR92_RS24450 2389248..2389532 + 285 WP_158304319.1 hypothetical protein Toxin
DR92_RS21565 2389529..2389810 + 282 WP_144243804.1 hypothetical protein Antitoxin
DR92_RS24455 2390488..2390634 - 147 WP_158304318.1 hypothetical protein -
DR92_RS21570 2390739..2394197 - 3459 WP_040129745.1 chromosome segregation protein SMC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10840.76 Da        Isoelectric Point: 10.8134

>T47623 WP_158304319.1 NZ_CP008820:2389248-2389532 [Brucella anthropi]
MSQSVEFMLLKTQWYLSRNWIRAKWKTGSNSIETQHLHLEFFLSAKVFPTKADRLMAIGEFNGQIIIVVVFKPIGSEALS
VISMRPASQKERKL

Download         Length: 285 bp

>T47623 NZ_CP008820:2389248-2389532 [Brucella anthropi]
ATGTCCCAGTCAGTTGAATTCATGCTCTTGAAAACACAATGGTATCTGTCTCGCAATTGGATCAGAGCGAAATGGAAAAC
TGGTTCAAACTCAATTGAAACTCAACACTTGCATTTAGAATTCTTCTTGTCGGCCAAGGTCTTCCCTACCAAGGCAGATC
GCTTGATGGCAATCGGCGAATTCAACGGTCAGATCATTATCGTCGTCGTCTTCAAGCCGATTGGTTCGGAAGCCCTCTCC
GTTATCTCCATGCGTCCAGCAAGCCAAAAGGAAAGGAAGCTATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10087.50 Da        Isoelectric Point: 6.4693

>AT47623 WP_144243804.1 NZ_CP008820:2389529-2389810 [Brucella anthropi]
MMGIKFSSKRPLTQEEEAAIQKMIASDPDAPEATDEQLAKAKPFKEALPEMAAWGQAKPLEPQSPSPGHEIFNFGHGTGL
LKLRAASSVDARR

Download         Length: 282 bp

>AT47623 NZ_CP008820:2389529-2389810 [Brucella anthropi]
ATGATGGGTATCAAATTTTCCTCTAAGCGCCCTCTCACTCAGGAAGAAGAGGCAGCAATCCAGAAGATGATCGCAAGTGA
TCCTGATGCGCCAGAAGCCACCGATGAACAACTTGCCAAGGCAAAACCCTTCAAAGAAGCCCTCCCGGAAATGGCCGCGT
GGGGTCAAGCAAAGCCTCTTGAACCACAGTCACCGTCCCCGGGGCATGAGATATTCAATTTTGGCCATGGTACAGGTCTC
CTCAAACTTCGTGCCGCATCGAGCGTGGATGCGCGCAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References