47580

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) fic-relB/Fic(toxin)
Location 1307953..1309709 Replicon chromosome
Accession NZ_CP008810
Organism Campylobacter fetus subsp. venerealis 97/608

Toxin (Protein)


Gene name Fic Uniprot ID C5H2Y4
Locus tag CFV97608_RS06685 Protein ID WP_002850956.1
Coordinates 1307953..1308873 (-) Length 307 a.a.

Antitoxin (Protein)


Gene name Fic Uniprot ID B2CG46
Locus tag CFV97608_RS06690 Protein ID WP_002850958.1
Coordinates 1308873..1309709 (-) Length 279 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFV97608_RS06655 1303107..1303457 - 351 WP_035170727.1 hypothetical protein -
CFV97608_RS06660 1303574..1304539 - 966 WP_035170725.1 hypothetical protein -
CFV97608_RS06665 1304536..1305291 - 756 WP_035170722.1 hypothetical protein -
CFV97608_RS06670 1305371..1305811 - 441 WP_035170721.1 hypothetical protein -
CFV97608_RS06675 1306338..1307675 + 1338 WP_035148452.1 hypothetical protein -
CFV97608_RS06680 1307684..1307953 - 270 WP_035148454.1 hypothetical protein -
CFV97608_RS06685 1307953..1308873 - 921 WP_002850956.1 Fic family protein Toxin
CFV97608_RS06690 1308873..1309709 - 837 WP_002850958.1 Fic family protein Antitoxin
CFV97608_RS10450 1309713..1310015 - 303 WP_080582791.1 DUF86 domain-containing protein -
CFV97608_RS06700 1310137..1310448 - 312 WP_002850963.1 nucleotidyltransferase domain-containing protein -
CFV97608_RS06705 1310516..1311178 - 663 WP_002850964.1 AAA family ATPase -
CFV97608_RS06710 1311203..1311520 - 318 WP_010400644.1 hypothetical protein -
CFV97608_RS06715 1311588..1312298 - 711 WP_002850968.1 hypothetical protein -
CFV97608_RS10330 1312501..1312716 - 216 WP_002850970.1 hypothetical protein -
CFV97608_RS10335 1312713..1312967 - 255 WP_010400630.1 hypothetical protein -
CFV97608_RS10695 1312964..1314184 - 1221 WP_002850972.1 hypothetical protein -
CFV97608_RS06735 1314181..1314678 - 498 WP_002850973.1 lytic transglycosylase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1259409..1314678 55269


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(91-202)

Antitoxin

Fido domain

(85-182)


Sequences

Toxin        


Download         Length: 307 a.a.        Molecular weight: 35445.26 Da        Isoelectric Point: 9.2339

>T47580 WP_002850956.1 NZ_CP008810:c1308873-1307953 [Campylobacter fetus subsp. venerealis 97/608]
MQEQYTEIKDSNIINKQNIDIAVGLGLVDDLKPSEYFYKAVEKSRTYNELEDNVKKYYDGKKLDKKEVGEKECDIVSVNI
AKYLEKSGFTLSPVTLKTIHKNLFWDAFPQGLEKYVGVFRDVNISKKEEVLGGEKSVEYGNYDELGDMLDYDFDREKRKD
YAKMTRQEQALNVGKFVSGVWQIHPFREGNTRTIAVFTIKYLQSKGFEANNDIFKENSKYFRDALVLANYDNMKENIKSD
FSYLESFFNKFILNKNIELKLLPNSPKGHKSEKSVLSRLGAAYDKKVQSGAIKQPQISKKSKEKER

Download         Length: 921 bp

>T47580 NZ_CP008810:c1308873-1307953 [Campylobacter fetus subsp. venerealis 97/608]
ATGCAAGAACAATATACGGAAATCAAAGATAGCAATATTATTAATAAACAAAACATAGATATTGCAGTAGGGCTTGGGCT
TGTAGATGATCTGAAGCCTTCTGAGTATTTTTATAAGGCTGTTGAAAAATCGCGAACATACAACGAACTTGAAGACAATG
TAAAGAAATATTATGATGGCAAAAAGCTAGATAAAAAAGAGGTCGGCGAAAAAGAGTGCGATATAGTTTCAGTAAATATC
GCCAAGTATTTAGAAAAAAGTGGCTTTACGCTATCTCCTGTTACATTGAAGACTATACATAAAAATTTATTTTGGGATGC
CTTTCCACAAGGGCTTGAAAAATATGTTGGAGTTTTTAGGGATGTAAATATTTCAAAAAAAGAAGAAGTCTTGGGTGGCG
AAAAAAGCGTAGAGTATGGTAATTATGATGAGCTTGGCGATATGCTGGATTATGATTTTGATAGAGAAAAACGCAAAGAT
TACGCCAAAATGACTAGGCAAGAACAGGCTTTAAATGTCGGCAAATTTGTAAGCGGGGTATGGCAAATTCATCCGTTTCG
AGAAGGCAATACTAGGACAATTGCGGTTTTTACTATTAAGTATCTGCAAAGTAAAGGCTTTGAAGCAAACAACGATATCT
TTAAAGAAAACTCAAAATATTTCAGGGATGCTTTAGTGTTAGCAAATTACGACAATATGAAAGAAAATATAAAAAGTGAT
TTTTCATACCTAGAGAGTTTTTTTAACAAATTTATTCTAAATAAAAATATAGAGTTAAAACTGCTACCAAACAGCCCAAA
AGGTCACAAAAGTGAGAAATCAGTCCTATCTAGACTTGGTGCAGCCTATGACAAAAAGGTGCAAAGTGGAGCGATCAAAC
AACCACAAATAAGCAAAAAATCAAAAGAAAAGGAAAGATAA

Antitoxin


Download         Length: 279 a.a.        Molecular weight: 31851.33 Da        Isoelectric Point: 8.5962

>AT47580 WP_002850958.1 NZ_CP008810:c1309709-1308873 [Campylobacter fetus subsp. venerealis 97/608]
MDGGVNLGNFLKNNNERDYWLDVCVRMAHHSTAIEGNTLSQDETASILLDGYIAKATSEREFYEVKNYRQILPKMFSSLQ
EKAKIDEKLIKDFHRLIMNNLIDNNGKFKTIENLVVGANFEPTKPYLVPVAIKDMCDNLYFRLDNAKNDDDKLKAILQSH
IKFEKIHPFSDGNGRTGRIIMIYGCLENNLAPIIIPKEQKNRYIAILRNNDIDGFMAFAKEIEKDEISRRNKFLSQRPNE
QDNSKSVLSRLGNAYAKKLESGAIKALNDTANSKEKER

Download         Length: 837 bp

>AT47580 NZ_CP008810:c1309709-1308873 [Campylobacter fetus subsp. venerealis 97/608]
ATGGATGGCGGTGTAAATTTAGGCAATTTCTTAAAAAACAACAACGAGCGAGACTATTGGCTAGATGTATGTGTTCGTAT
GGCTCATCATAGCACAGCAATCGAGGGCAATACTTTAAGTCAGGATGAGACTGCTTCAATCTTGCTTGATGGCTATATAG
CAAAAGCAACTAGCGAGCGTGAATTTTATGAAGTAAAAAACTATCGCCAAATTTTGCCAAAAATGTTTTCATCTTTACAA
GAAAAAGCCAAGATAGACGAGAAGCTAATAAAAGATTTTCATAGGCTAATAATGAATAATTTAATAGACAACAACGGCAA
ATTTAAAACTATCGAAAATTTAGTTGTAGGCGCAAATTTCGAACCTACAAAGCCGTATCTAGTGCCAGTAGCAATTAAAG
ATATGTGCGATAATCTATATTTTAGACTTGATAATGCCAAAAATGACGACGATAAGCTAAAAGCAATATTGCAAAGCCAT
ATCAAATTTGAAAAAATTCATCCTTTTAGTGACGGAAACGGCAGAACCGGCAGGATAATTATGATCTATGGTTGTTTAGA
GAATAATTTAGCACCAATTATAATACCAAAAGAGCAAAAAAATAGATACATTGCAATACTGCGCAACAATGACATCGATG
GATTTATGGCGTTTGCTAAAGAAATAGAAAAAGATGAAATATCAAGGCGTAATAAATTTTTAAGCCAACGACCAAATGAG
CAAGATAATAGTAAATCAGTCTTATCTAGGCTCGGCAATGCTTACGCCAAAAAGCTAGAAAGCGGAGCGATCAAAGCATT
AAATGATACCGCAAATTCAAAGGAAAAGGAGAGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7D7L3Y5

Antitoxin

Source ID Structure
AlphaFold DB A0A7D7Q668

References