Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2429412..2429683 Replicon chromosome
Accession NZ_CP008805
Organism Escherichia coli O157:H7 str. SS17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2429450..2429553 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2429412..2429683 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SS17_RS12520 2426569..2428008 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SS17_RS12525 2428126..2428362 + 237 WP_001295499.1 DUF1480 family protein -
SS17_RS12530 2428467..2428658 + 192 WP_001296140.1 YebW family protein -
SS17_RS12535 2428659..2429315 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2429412..2429683 + 272 - - Antitoxin
- 2429450..2429553 - 104 - - Toxin
SS17_RS12545 2429711..2430052 - 342 WP_000976483.1 YebY family protein -
SS17_RS12550 2430065..2430937 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
SS17_RS12555 2430941..2431315 - 375 WP_000168751.1 CopC domain-containing protein YobA -
SS17_RS12560 2431454..2431684 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SS17_RS12565 2431786..2432442 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
SS17_RS12570 2432466..2433128 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T47554 NZ_CP008805:c2429553-2429450 [Escherichia coli O157:H7 str. SS17]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT47554 NZ_CP008805:2429412-2429683 [Escherichia coli O157:H7 str. SS17]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References