47473

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2445086..2445231 Replicon chromosome
Accession NZ_CP008797
Organism Klebsiella pneumoniae subsp. pneumoniae KPNIH24

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2445122..2445224 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2445086..2445231 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPNIH24_RS12130 2440216..2442276 + 2061 WP_032422099.1 oligopeptidase B -
KPNIH24_RS12135 2442280..2442939 - 660 WP_002911407.1 exodeoxyribonuclease X -
KPNIH24_RS12140 2443018..2443248 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KPNIH24_RS12145 2443361..2443735 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KPNIH24_RS12150 2443739..2444608 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KPNIH24_RS12155 2444625..2444963 + 339 WP_002911404.1 YebY family protein -
- 2445086..2445231 - 146 - - Antitoxin
- 2445122..2445224 + 103 - - Toxin
KPNIH24_RS31365 2445599..2445742 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KPNIH24_RS12165 2445847..2446815 - 969 WP_004151446.1 VirK/YbjX family protein -
KPNIH24_RS12170 2446972..2447625 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
KPNIH24_RS12175 2447622..2447813 - 192 WP_002911395.1 YebW family protein -
KPNIH24_RS12180 2447911..2448150 - 240 WP_002911393.1 YebV family protein -
KPNIH24_RS12185 2448266..2449699 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T47473 NZ_CP008797:2445122-2445224 [Klebsiella pneumoniae subsp. pneumoniae KPNIH24]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT47473 NZ_CP008797:c2445231-2445086 [Klebsiella pneumoniae subsp. pneumoniae KPNIH24]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References