Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4616620..4617089 Replicon chromosome
Accession NZ_CP008742
Organism Pseudomonas savastanoi pv. savastanoi NCPPB 3335

Toxin (Protein)


Gene name relE Uniprot ID Q48BA0
Locus tag PSA3335_RS21980 Protein ID WP_002556029.1
Coordinates 4616620..4616901 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q48BA1
Locus tag PSA3335_RS21985 Protein ID WP_002556028.1
Coordinates 4616901..4617089 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSA3335_RS21960 4611732..4613246 + 1515 WP_054082386.1 IS21 family transposase -
PSA3335_RS21965 4613267..4614022 + 756 WP_002552598.1 IS21-like element ISPsy14 family helper ATPase IstB -
PSA3335_RS29440 4614126..4614443 - 318 Protein_4115 transposase zinc-binding domain-containing protein -
PSA3335_RS21975 4614839..4616320 + 1482 WP_002556030.1 hypothetical protein -
PSA3335_RS21980 4616620..4616901 - 282 WP_002556029.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSA3335_RS21985 4616901..4617089 - 189 WP_002556028.1 hypothetical protein Antitoxin
PSA3335_RS21990 4617266..4617857 - 592 Protein_4119 recombinase family protein -
PSA3335_RS21995 4617898..4618317 - 420 WP_082301344.1 type II toxin-antitoxin system VapC family toxin -
PSA3335_RS22000 4618314..4618571 - 258 WP_003381346.1 Arc family DNA-binding protein -
PSA3335_RS22010 4619102..4620601 + 1500 WP_122302115.1 IS21-like element ISPsy20 family transposase -
PSA3335_RS22015 4620594..4621397 + 804 WP_031598096.1 IS21-like element ISPsy20 family helper ATPase IstB -
PSA3335_RS22020 4621553..4621681 - 129 Protein_4124 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4611732..4659897 48165


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10675.35 Da        Isoelectric Point: 8.4392

>T47336 WP_002556029.1 NZ_CP008742:c4616901-4616620 [Pseudomonas savastanoi pv. savastanoi NCPPB 3335]
MLPVVWLSPALDDLREIATYIAWENPSAARRLKSLLQEAIEPVAEHPYLYRSGRAPGTRELVAHPNYVLVYRVTLKRIEV
VNVIHARQEYPSP

Download         Length: 282 bp

>T47336 NZ_CP008742:c4616901-4616620 [Pseudomonas savastanoi pv. savastanoi NCPPB 3335]
ATGCTGCCGGTGGTCTGGCTCAGTCCCGCACTGGATGATCTGCGCGAAATCGCAACCTACATCGCATGGGAAAACCCGAG
CGCAGCGCGCCGGTTGAAAAGCCTCCTGCAGGAGGCTATCGAGCCGGTAGCCGAACACCCCTATTTATATCGTTCTGGGC
GAGCGCCAGGCACTCGCGAGCTGGTGGCTCATCCAAACTACGTCCTGGTCTATCGTGTCACCCTCAAGCGCATCGAGGTC
GTGAACGTAATCCACGCTAGGCAGGAATACCCCTCTCCCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7043.86 Da        Isoelectric Point: 4.2550

>AT47336 WP_002556028.1 NZ_CP008742:c4617089-4616901 [Pseudomonas savastanoi pv. savastanoi NCPPB 3335]
MANLSPIVSEFETDEQAASYDRWFRAKVAASLADPRPAIPHDEVMAEIEALIDQVETQREKR

Download         Length: 189 bp

>AT47336 NZ_CP008742:c4617089-4616901 [Pseudomonas savastanoi pv. savastanoi NCPPB 3335]
ATGGCCAACCTCTCACCCATCGTTTCAGAATTCGAAACCGATGAACAGGCCGCAAGCTACGACCGCTGGTTTCGCGCCAA
GGTCGCCGCCAGTCTGGCCGATCCGCGTCCGGCCATCCCTCACGATGAGGTCATGGCGGAAATAGAAGCGCTGATCGATC
AGGTTGAAACCCAACGTGAGAAACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M9HVA1

Antitoxin

Source ID Structure
AlphaFold DB A0A2G9KWB9

References