Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 330791..331310 Replicon chromosome
Accession NZ_CP008742
Organism Pseudomonas savastanoi pv. savastanoi NCPPB 3335

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag PSA3335_RS01590 Protein ID WP_002551445.1
Coordinates 331020..331310 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag PSA3335_RS01585 Protein ID WP_002551444.1
Coordinates 330791..331030 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSA3335_RS01565 327541..328815 + 1275 WP_002551441.1 OprD family porin -
PSA3335_RS01570 328849..329343 - 495 WP_004667254.1 hypothetical protein -
PSA3335_RS01575 329540..330052 + 513 WP_031598429.1 GNAT family N-acetyltransferase -
PSA3335_RS01580 330154..330627 + 474 WP_002551443.1 GNAT family N-acetyltransferase -
PSA3335_RS01585 330791..331030 + 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PSA3335_RS01590 331020..331310 + 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSA3335_RS01600 331543..332280 - 738 WP_002551446.1 hypothetical protein -
PSA3335_RS01605 332457..333437 + 981 WP_044424202.1 IS5 family transposase -
PSA3335_RS01610 333757..334179 - 423 WP_005746664.1 DUF1493 family protein -
PSA3335_RS01620 334653..335141 + 489 WP_002551447.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T47332 WP_002551445.1 NZ_CP008742:331020-331310 [Pseudomonas savastanoi pv. savastanoi NCPPB 3335]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

>T47332 NZ_CP008742:331020-331310 [Pseudomonas savastanoi pv. savastanoi NCPPB 3335]
ATGACCTATAACCTCGAATTCGATGCGCGGGCTCTAAAGGAATGGCACAAATTAGGAGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCCAATCGTCTGCATGCATTGCCTGACTGCTACAAAATCA
AACTGCGCAGTAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCGGTAGACAAG
CGTGAACGGGAAGAGGTTTATCGCAAGGCGACGGACCGGCTGGGTAGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT47332 WP_002551444.1 NZ_CP008742:330791-331030 [Pseudomonas savastanoi pv. savastanoi NCPPB 3335]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT47332 NZ_CP008742:330791-331030 [Pseudomonas savastanoi pv. savastanoi NCPPB 3335]
ATGGCGTCTATCAACGTTCGTATCGACGACGATCTCAAAGCGCGTGCTTACCTCGAGCTGGAAAAGCTTGGCGTCACCCC
CTCGGAGTTGCTGCGCCAAACCCTGCAGTACGTAGCTGAGCGTGGTCAGCTACCCTTCAAGACGGTTCTGATGACAGAGG
AAGACGAAGCGCTGTTGGCAACTGTGCGCGAGCGCCTTGCAGCTCCGCAGCGGGTCAAGGTTTCACTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References