Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4285368..4285753 Replicon chromosome
Accession NZ_CP008714
Organism Xanthomonas translucens pv. undulosa strain Xtu 4699

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag FD63_RS17890 Protein ID WP_003469322.1
Coordinates 4285368..4285502 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag FD63_RS17895 Protein ID WP_003469323.1
Coordinates 4285601..4285753 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FD63_RS17875 4281800..4282723 - 924 WP_003469319.1 MBL fold metallo-hydrolase -
FD63_RS17880 4282793..4284193 - 1401 WP_003469320.1 tryptophan--tRNA ligase -
FD63_RS17885 4284304..4285158 + 855 WP_047325437.1 hypothetical protein -
FD63_RS17890 4285368..4285502 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
FD63_RS17895 4285601..4285753 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
FD63_RS17900 4285898..4286820 - 923 Protein_3630 arginase -
FD63_RS17910 4287226..4288044 - 819 WP_047325438.1 SPOR domain-containing protein -
FD63_RS17915 4288054..4288794 - 741 WP_047325439.1 type III pantothenate kinase -
FD63_RS17920 4288791..4289810 - 1020 WP_162489024.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
FD63_RS17925 4289915..4290178 + 264 WP_038238001.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T47283 WP_003469322.1 NZ_CP008714:c4285502-4285368 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T47283 NZ_CP008714:c4285502-4285368 [Xanthomonas translucens pv. undulosa]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT47283 WP_003469323.1 NZ_CP008714:c4285753-4285601 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT47283 NZ_CP008714:c4285753-4285601 [Xanthomonas translucens pv. undulosa]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References