Detailed information of TA system TA047282

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 1004359..1004864
• Replicon: chromosome
• Accession: NZ_CP008714
• Organism: Xanthomonas translucens pv. undulosa strain Xtu 4699

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FD63_RS04360
• Protein ID: WP_047324602.1
• Coordinates: 1004359..1004616 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: FD63_RS04365
• Protein ID: WP_003468816.1
• Coordinates: 1004613..1004864 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FD63_RS04330	999591..1000940	+	1350	WP_047324600.1	aminodeoxychorismate synthase component I	-
FD63_RS04335	1001010..1002077	+	1068	WP_173427093.1	endolytic transglycosylase MltG	-
FD63_RS04340	1002074..1002742	+	669	WP_047324601.1	dTMP kinase	-
FD63_RS04345	1002739..1003716	+	978	WP_003468812.1	DNA polymerase III subunit delta'	-
FD63_RS04350	1003713..1004066	+	354	WP_003468813.1	PilZ domain-containing protein	-
FD63_RS04360	1004359..1004616	-	258	WP_047324602.1	Txe/YoeB family addiction module toxin	Toxin
FD63_RS04365	1004613..1004864	-	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
FD63_RS04370	1005020..1005784	+	765	WP_003468819.1	endonuclease	-
FD63_RS04375	1005781..1006503	-	723	WP_003468821.1	ArsR family transcriptional regulator	-
FD63_RS04380	1006627..1007076	+	450	WP_003468823.1	nuclear transport factor 2 family protein	-
FD63_RS04385	1007329..1007934	+	606	WP_047325549.1	hypothetical protein	-
FD63_RS04390	1008102..1008377	-	276	WP_003468826.1	hypothetical protein	-
FD63_RS04395	1008712..1009002	+	291	WP_003468827.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10159.61 Da
• Isoelectric Point: 9.3202

>T47282 WP_047324602.1 NZ_CP008714:c1004616-1004359 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDYLYWQQTDKKMLNRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Nucleotide

• Length: 258 bp

>T47282 NZ_CP008714:c1004616-1004359 [Xanthomonas translucens pv. undulosa]
GTGACGCTTCAGTTCTCGGACAATGCCTGGGAGGACTACCTCTACTGGCAGCAGACCGACAAGAAGATGCTCAATCGCAT
CAACGACCTGATCAAAGCCATTCAACGCGATCCCTTCCAGGGCGTCGGCAAGCCAGAACCGCTACGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGCATCAACGACGAACATCGCATCGTGTACAAGGTCGAGGCGGGCGTCCTGCTGATCGCGCAGGTG
CGCTACCACTACGTGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT47282 WP_003468816.1 NZ_CP008714:c1004864-1004613 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT47282 NZ_CP008714:c1004864-1004613 [Xanthomonas translucens pv. undulosa]
ATGGACACCATCACCTATAGCGCTGCACGCGCCGCCCTTGCGGACACCATGGAGCGCGTCGTCAACAACCACGAGCCGGT
GATCATCACCCGCAGCCGCGAGCAATCCGTGGTCATGCTGTCGCTTGAAGACTACAAGGCGATGGAGGAAACCGCCTACC
TGCTCCGCAGTCCGAAGAGCGCGCAGCGCCTGCTGGAATCCATCGCCCAGCTCGAGGCCGGTCGCGGCAAGGCACGGGAC
CTGGCCGAGTGA

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9