Detailed information of TA system TA047215

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PemK-MazE
• Location: 4344080..4344621
• Replicon: chromosome
• Accession: NZ_CP007810
• Organism: Xanthomonas oryzae pv. oryzicola strain YM15

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: FE36_RS19120
• Protein ID: WP_015462614.1
• Coordinates: 4344295..4344621 (+)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: H8FMA7
• Locus tag: FE36_RS19115
• Protein ID: WP_003491150.1
• Coordinates: 4344080..4344298 (+)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FE36_RS19090	4339787..4341007	+	1221	WP_047340366.1	TrbI/VirB10 family protein	-
FE36_RS19095	4341018..4342040	+	1023	WP_047340367.1	P-type DNA transfer ATPase VirB11	-
FE36_RS19100	4342027..4342935	+	909	WP_047340368.1	lytic transglycosylase domain-containing protein	-
FE36_RS19105	4343060..4343479	+	420	WP_047340369.1	hypothetical protein	-
FE36_RS19110	4343556..4343942	+	387	WP_047340370.1	hypothetical protein	-
FE36_RS19115	4344080..4344298	+	219	WP_003491150.1	antitoxin MazE family protein	Antitoxin
FE36_RS19120	4344295..4344621	+	327	WP_015462614.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
FE36_RS19125	4344690..4347665	-	2976	WP_047340371.1	conjugative relaxase	-
FE36_RS19130	4347679..4349253	-	1575	WP_047340372.1	type IV secretion system DNA-binding domain-containing protein	-
FE36_RS23250	4349257..4349430	-	174	WP_164722239.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	4108519..4388409	279890

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (3-103)

Antitoxin

• Antitoxin MazE-like (5-70)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 11676.70 Da
• Isoelectric Point: 9.2550

>T47215 WP_015462614.1 NZ_CP007810:4344295-4344621 [Xanthomonas oryzae pv. oryzicola]
MMRGDFVTIAMQGDFGKPRPALVIQADQFDAHTTVTVLPVTSTLVAAPLLRITVHPSTDNGLQKPSQVMVDKAMTVKRDK
VGRAFGRVDADALVEIERCLAVFLGIAK

Nucleotide

• Length: 327 bp

>T47215 NZ_CP007810:4344295-4344621 [Xanthomonas oryzae pv. oryzicola]
ATGATGCGGGGTGACTTTGTGACCATCGCCATGCAAGGCGACTTCGGAAAACCACGGCCCGCTCTGGTGATCCAGGCCGA
CCAGTTTGACGCACACACCACCGTGACGGTGCTGCCGGTGACAAGCACGCTCGTTGCTGCGCCGCTGCTGCGCATTACCG
TTCATCCAAGTACCGACAATGGTTTGCAGAAGCCGTCTCAGGTGATGGTGGACAAGGCCATGACCGTGAAGCGTGACAAG
GTAGGTCGAGCCTTTGGGCGCGTAGACGCTGATGCGTTGGTGGAAATTGAGCGCTGCCTGGCCGTGTTCTTGGGCATCGC
TAAGTGA

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 8418.54 Da
• Isoelectric Point: 5.6599

>AT47215 WP_003491150.1 NZ_CP007810:4344080-4344298 [Xanthomonas oryzae pv. oryzicola]
MAHVNSRVQKHRDALRMAGLRPVQIWVPDTRRPDFAEECRRQCRLAAQADMADTDMQRFMDEALADMDGWTE

Nucleotide

• Length: 219 bp

>AT47215 NZ_CP007810:4344080-4344298 [Xanthomonas oryzae pv. oryzicola]
ATGGCACACGTCAATTCACGAGTTCAAAAGCACCGCGACGCCCTGCGCATGGCAGGGCTGCGTCCGGTGCAAATTTGGGT
GCCGGACACACGGCGGCCTGACTTCGCCGAGGAATGCCGCCGTCAGTGTCGTCTTGCTGCACAAGCGGACATGGCGGACA
CCGACATGCAGCGCTTCATGGATGAGGCGCTAGCAGACATGGATGGCTGGACGGAATGA

Structures

Antitoxin

• AlphaFold DB: H8FMA7