Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) omega-epsilon-zeta/-
Location 3730312..3731891 Replicon chromosome
Accession NZ_CP007810
Organism Xanthomonas oryzae pv. oryzicola strain YM15

Toxin (Protein)


Gene name avrRxo1 Uniprot ID A0A5E8KQ48
Locus tag FE36_RS16360 Protein ID WP_047340211.1
Coordinates 3730626..3731891 (-) Length 422 a.a.

Antitoxin (Protein)


Gene name arc1 Uniprot ID A0A0C5UZA4
Locus tag FE36_RS16355 Protein ID WP_044749828.1
Coordinates 3730312..3730608 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE36_RS16345 3725532..3726284 + 753 WP_024712407.1 YceI family protein -
FE36_RS21790 3726500..3726675 - 176 Protein_3266 HAD family hydrolase -
FE36_RS22785 3726770..3726847 - 78 Protein_3267 anti-sigma factor antagonist -
FE36_RS16350 3727365..3730052 + 2688 WP_014504812.1 pyruvate dehydrogenase (acetyl-transferring), homodimeric type -
FE36_RS16355 3730312..3730608 - 297 WP_044749828.1 hypothetical protein Antitoxin
FE36_RS16360 3730626..3731891 - 1266 WP_047340211.1 avirulence protein Toxin
FE36_RS21800 3732046..3732353 - 308 Protein_3271 hemagglutinin repeat-containing protein -
FE36_RS21810 3732706..3732978 + 273 WP_076342625.1 type I toxin-antitoxin system SymE family toxin -
FE36_RS22790 3733982..3734647 - 666 Protein_3273 hemagglutinin repeat-containing protein -
FE36_RS21815 3734693..3734809 + 117 Protein_3274 IS30 family transposase -
FE36_RS22795 3734855..3735073 - 219 WP_076342548.1 immunity protein 31 -
FE36_RS21820 3735070..3735732 - 663 WP_178385938.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(149-291)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 422 a.a.        Molecular weight: 45159.73 Da        Isoelectric Point: 6.9140

>T47213 WP_047340211.1 NZ_CP007810:c3731891-3730626 [Xanthomonas oryzae pv. oryzicola]
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAATHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI

Download         Length: 1266 bp

>T47213 NZ_CP007810:c3731891-3730626 [Xanthomonas oryzae pv. oryzicola]
ATGAAAAACAAGACAGACATTGCTGGCATAGCCGGACTTTCTACGTCTCATGTTTCCTTTGATGACGCAGAATCCAAAAG
CGTCCTAGATGGATCAACACAGTCTACGCCGGAGTACAAATTCCAGACCCCGCTTGATCAGTTGCCGGCTAGGCCCGCTG
GTCCGAAGAGCAGTAACACAACTGATGCTTACATTCATGAATCACTGCCGCATTCGGTTCCAATCGCAGGTGCATCGACC
TCCGCGGCGACACATCAACAGGCTACTCAGCGTAAAGGCACCGATGAGATCTATGGTTTGGGCAGCCTCCCATCTGCTGG
TCCAGAGCGATGGGATTATCTTGCGAATCCGGGGAACTGGCATCCCGAACGCCGTAAGTTACACGAAAAGCTATTAGATC
AAGCGCGATCTTCTGCCTTGACCCTGGCAGAATCCCTTGAGAGTGATGGCTGCCAACCGACATTGTTTGCGCTGCGCGGA
AATACCGCAACGGGTAAAACACGGATTGCGACAAAAAAGATCCCGGTGCTCGCAGCAGCTCTGAAGAAGACAGGTGGGAA
AGGTTGCGTGAATCCAGATGTATTCAAGAGTTCGCTTGCGAAATCCGAGGCAGGCGCCAAGATATTTAGTTCGGCACAAG
TGCATAGCGAGTCATCTTTTCTTGCCGACCGGTTTGAAGGCGGACTTCGCTCTCAAAAGACGGGCAGCGGTGCAATCGCT
AGCATTGTTGTCGACAAGCGCTTGTCAAGAGCGTACGAAATTGATAGCTACATACAACTAGCGAAAGAAACCGGTAGAAA
AGTGGAATTGTGCGATATCGACGCGCCCCTAGAGAATTCTTTGGTGGGAGTTTTGCAGCGAAAACCGGAAGGTGAAGATC
CTAGGCCTCCGTACCCTGTAGTCTCGAGTGGATTTGTAGCCGTACGGAGCAATAGAATGTACGTGATAGACAGGTTCATT
GCCGATCCGAGCCTGGGAAACTACCGACTATTCGGAACAGCTGAAGATGGTGAGAAGGTCATGGTTGCTAGCGTGATTGG
CGGTGAGTTTAGTGTAGAGAATGCTGAGTTGTATGAAAAAATCACGTCCCCACAGCTCTCGGTTACGGGCGATTTGGCTG
ATAAGGTAATCGACAAGGAATTGATTGATCGTCTGAAAAATAATATAGCTGACCCCGAGCGGGCGGCCAAGACGCAAGCC
GCCCTGGAAAAATACAGCGGTAAGTCATGGTCGGCCGCGCTAGCTGCTCACAGCGAGCTAATTTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11327.83 Da        Isoelectric Point: 5.2138

>AT47213 WP_044749828.1 NZ_CP007810:c3730608-3730312 [Xanthomonas oryzae pv. oryzicola]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS

Download         Length: 297 bp

>AT47213 NZ_CP007810:c3730608-3730312 [Xanthomonas oryzae pv. oryzicola]
ATGAAAACTTTGACAGGCGCAGACGCACTCGAATTTCATAAGAAGCTTAAGGAACGTAATAAAGCCTTACATGCTTCCGA
CCTCGAGTTAGCACTGGTGCACGCCGATGCTGTCGGCAAAGAACGGTTCGATCTCGAGGAGCTGGAGAAAATTTGCGATA
CCAGCGATGCGGGGCGCCTTACTGATGCGAAAGAGCGACACGACATATATGAAAGGATGTACTACGTTGAGTATCCCAAC
GTTATGACGTTAAAGGAATTCGCTCATATCGTCGAGACACTTTCCTCGTGGTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5E8KQ48

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5UZA4

References