Detailed information of TA system TA047212

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 3457008..3458689
• Replicon: chromosome
• Accession: NZ_CP007810
• Organism: Xanthomonas oryzae pv. oryzicola strain YM15

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: FE36_RS15170
• Protein ID: WP_047340151.1
• Coordinates: 3457008..3457622 (+)
• Length: 205 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: A0A5E8KSB4
• Locus tag: FE36_RS15175
• Protein ID: WP_047340152.1
• Coordinates: 3457619..3458689 (+)
• Length: 357 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FE36_RS15150	3452927..3453577	+	651	WP_024710589.1	SGNH/GDSL hydrolase family protein	-
FE36_RS15155	3453900..3454571	+	672	WP_047340150.1	class I SAM-dependent methyltransferase	-
FE36_RS15160	3454875..3455666	-	792	WP_024710587.1	polysaccharide deacetylase family protein	-
FE36_RS15165	3455712..3456638	+	927	WP_024710586.1	Grx4 family monothiol glutaredoxin	-
FE36_RS15170	3457008..3457622	+	615	WP_047340151.1	DUF4433 domain-containing protein	Toxin
FE36_RS15175	3457619..3458689	+	1071	WP_047340152.1	macro domain-containing protein	Antitoxin
FE36_RS15180	3458798..3459358	-	561	WP_044750878.1	DUF924 family protein	-
FE36_RS15185	3459498..3460907	+	1410	WP_047340153.1	amidohydrolase	-
FE36_RS15190	3460904..3462184	+	1281	WP_024710581.1	amidohydrolase family protein	-
FE36_RS15195	3462488..3462814	+	327	WP_024710580.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-203)

Antitoxin

• Macro domain (18-129)

Sequences

Toxin

Protein

• Length: 205 a.a.
• Molecular weight: 23714.94 Da
• Isoelectric Point: 7.5676

>T47212 WP_047340151.1 NZ_CP007810:3457008-3457622 [Xanthomonas oryzae pv. oryzicola]
MIWRITHRGNLPWILDNGLHCGNAAVQSSSWVSIGNPELIDKRSSHPVPLPPGGFSNDYVPFYFTPFLPMLRNIHTAWGG
IQRRPNEDIVILVSSLHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIH
RHVPLDGLRGIVCHTDGLQQTIERQLQERNLKLPVHTRTGWYFR

Nucleotide

• Length: 615 bp

>T47212 NZ_CP007810:3457008-3457622 [Xanthomonas oryzae pv. oryzicola]
CTGATCTGGCGCATCACCCACCGGGGCAATCTGCCGTGGATTCTGGACAACGGTCTGCACTGTGGTAATGCCGCTGTGCA
GAGTTCGAGTTGGGTGAGCATCGGCAACCCAGAACTGATCGACAAGCGCTCCAGTCATCCTGTACCGCTTCCACCGGGCG
GCTTCTCAAACGATTACGTGCCGTTCTACTTCACTCCGTTTTTGCCGATGCTGCGCAACATCCATACCGCCTGGGGTGGA
ATCCAAAGGCGGCCTAACGAAGACATCGTCATCCTTGTTTCCAGCTTGCATCATGTCGCCGAACGCCGATGGCCGTTTCT
GTTTACTGACAGCCACGCCTACTGCCAGTTGGCGAGCTTCTATTCCGATTTATCCGATCTCGACAAGATCGACTGGCCGT
TGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCAGCCAAGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCAC
CGACACGTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCATACGGATGGTTTGCAACAGACCATCGAGCGGCAACTCCA
AGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGGGTGGTATTTCCGATGA

Antitoxin

Protein

• Length: 357 a.a.
• Molecular weight: 39970.97 Da
• Isoelectric Point: 6.0089

>AT47212 WP_047340152.1 NZ_CP007810:3457619-3458689 [Xanthomonas oryzae pv. oryzicola]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDRADVRPLIEEVLAGLDTDILVFEPTLKYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECGLLEIQKLAWFLERNIERAGLPELDLRFSAHKYGPYADRLRHLLNGLDGSYLHCD
KRISDADPLDVIWFDDNRKSFVQTYLKSEAKQYIPALEATAALIDGFESPFGMELLATVDWLIVQEGISAQVADVREGIR
HWPGDQEAAARKDRLFDDRALGIALKRLASGAIAVA

Nucleotide

• Length: 1071 bp

>AT47212 NZ_CP007810:3457619-3458689 [Xanthomonas oryzae pv. oryzicola]
ATGATCACGTTCACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCGTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACCGGGCCGACGTGCGCCCACTGATCGAAG
AAGTACTAGCAGGTTTGGATACAGACATCCTCGTGTTCGAGCCTACCTTGAAGTATCAGAACGTTGCCAAGCGCTCCGGC
GTGGAAAAATTGACCCCGGCACGCGCCTTGATTGCCGAGCTGGTACGTCGTTACTGGGTGCTAGGTATGGAATGCGGCCT
GTTGGAAATCCAGAAACTGGCGTGGTTCCTTGAACGCAACATCGAGCGAGCGGGCTTGCCTGAGCTTGATTTGCGCTTTT
CAGCACACAAGTACGGCCCTTATGCCGACCGTCTACGCCATCTTCTGAACGGGCTGGACGGAAGCTACCTGCATTGTGAC
AAACGGATCAGCGACGCCGACCCGCTGGACGTGATCTGGTTCGACGACAATCGCAAAAGCTTCGTACAGACCTACCTAAA
GAGCGAGGCGAAACAGTACATTCCAGCACTGGAAGCTACTGCCGCCTTGATCGATGGTTTTGAATCTCCTTTTGGCATGG
AGTTGTTGGCGACAGTTGACTGGCTGATTGTGCAGGAAGGTATCTCTGCGCAAGTTGCCGACGTGCGTGAAGGCATACGC
CACTGGCCAGGTGATCAGGAGGCAGCGGCGCGAAAGGACAGACTGTTCGATGACCGCGCCTTGGGGATCGCGCTGAAACG
ACTGGCATCAGGTGCAATCGCAGTGGCTTAA

Structures

Antitoxin

• AlphaFold DB: A0A5E8KSB4