Detailed information of TA system TA047000

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 1403339..1404470
• Replicon: chromosome
• Accession: NZ_CP007774
• Organism: Campylobacter volucris LMG 24379

Toxin (Protein)

• Gene name: panT
• Uniprot ID: A0A5C8KXZ5
• Locus tag: CVOL_RS07230
• Protein ID: WP_039666119.1
• Coordinates: 1403339..1404052 (-)
• Length: 238 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: CVOL_RS07235
• Protein ID: WP_039666120.1
• Coordinates: 1404042..1404470 (-)
• Length: 143 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CVOL_RS07210	1398697..1399347	-	651	WP_039666115.1	NAD-independent L-lactate dehydrogenase subunit	-
CVOL_RS07215	1399340..1400755	-	1416	WP_039666116.1	iron-sulfur cluster-binding protein	-
CVOL_RS07220	1400752..1401489	-	738	WP_039666117.1	NAD-independent L-lactate dehydrogenase, oxidoreductase subunit	-
CVOL_RS07225	1401498..1403153	-	1656	WP_039666118.1	L-lactate permease	-
CVOL_RS07230	1403339..1404052	-	714	WP_039666119.1	hypothetical protein	Toxin
CVOL_RS07235	1404042..1404470	-	429	WP_039666120.1	DUF4065 domain-containing protein	Antitoxin
CVOL_RS07240	1404611..1406410	-	1800	WP_039666121.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (24-117)

Sequences

Toxin

Protein

• Length: 238 a.a.
• Molecular weight: 28025.80 Da
• Isoelectric Point: 6.6867

>T47000 WP_039666119.1 NZ_CP007774:c1404052-1403339 [Campylobacter volucris LMG 24379]
MSFKKEHKELKVIIEKIYNEQSLESSCDDIVEKLITIYKTEYKHKYSELTTIILNITKSDREQDLMTLAQNVRMLEEKLD
NKTCDECIKEKIKDFYDHINLECVRLQDSDGKIKKIKDEYNELYKNYNNIKDNLSKQQTQYITILGIFASIVLTFVSGLV
FSTSVLSNIDKVSIFRLIFTMAFIAFFVGNILYSLFAFLLKISSIYSCKSNIYIYVFNLIIFLIMLIDFCFYLYCFY

Nucleotide

• Length: 714 bp

>T47000 NZ_CP007774:c1404052-1403339 [Campylobacter volucris LMG 24379]
ATGAGTTTTAAAAAAGAACATAAGGAACTAAAAGTAATTATAGAAAAAATATATAATGAGCAAAGCTTAGAAAGTAGTTG
TGATGACATTGTAGAAAAATTAATCACAATTTATAAAACAGAATATAAGCATAAGTATTCAGAGCTTACGACGATAATAT
TAAATATTACAAAAAGCGATAGAGAGCAAGATTTAATGACATTAGCTCAAAATGTTAGAATGCTTGAAGAAAAATTAGAT
AACAAAACTTGCGATGAGTGTATTAAAGAAAAAATTAAAGATTTTTATGATCATATTAATTTAGAGTGTGTCAGGTTACA
AGATTCTGATGGTAAAATAAAAAAGATAAAAGATGAATATAATGAGCTTTATAAAAATTACAATAATATAAAAGATAACC
TTAGTAAGCAACAAACTCAATATATTACTATTTTAGGTATTTTTGCTTCTATTGTTTTGACTTTTGTTAGCGGTTTGGTT
TTTTCAACTTCTGTATTGTCAAATATAGATAAAGTAAGTATTTTTAGATTAATTTTTACTATGGCTTTTATAGCTTTTTT
TGTAGGAAATATTCTTTATTCTTTATTTGCTTTTCTTTTAAAAATTTCTTCAATATATAGTTGTAAAAGTAATATTTACA
TTTATGTTTTTAATTTAATTATATTTTTAATTATGCTTATTGATTTTTGTTTTTATTTGTATTGTTTTTATTAA

Antitoxin

Protein

• Length: 143 a.a.
• Molecular weight: 16908.10 Da
• Isoelectric Point: 5.3615

>AT47000 WP_039666120.1 NZ_CP007774:c1404470-1404042 [Campylobacter volucris LMG 24379]
MVNALDLAKYILYKSDKDLSNLELQKTLYFTELDYIKKFDKHLINDDFEAWKYGPVARDVYCEYRNYGANSIDKPNDEIQ
LNLDNDELEIINNSIKKCNKQSYWILVEKSHRKGGAWEQSFKENKKEVINKELIKQEAKNEF

Nucleotide

• Length: 429 bp

>AT47000 NZ_CP007774:c1404470-1404042 [Campylobacter volucris LMG 24379]
ATGGTTAATGCTTTAGATTTAGCAAAATATATTCTTTATAAATCAGATAAAGATTTGAGTAATTTAGAACTACAAAAAAC
TTTATATTTTACAGAACTTGATTATATTAAAAAATTTGATAAACATCTTATTAATGATGATTTTGAAGCTTGGAAGTATG
GTCCTGTTGCTAGAGATGTTTATTGCGAATATAGAAATTATGGGGCTAATTCTATAGATAAACCTAACGATGAAATTCAA
TTAAATCTTGATAATGATGAGTTGGAAATAATTAATAATTCGATTAAAAAATGCAATAAACAATCTTATTGGATTCTTGT
TGAAAAAAGTCATAGAAAAGGTGGAGCGTGGGAGCAGAGTTTTAAAGAAAATAAAAAGGAAGTTATCAATAAGGAATTAA
TAAAACAAGAAGCCAAAAATGAGTTTTAA

Structures

Toxin

• AlphaFold DB: A0A5C8KXZ5